急性脑梗死患者低频重复经颅磁刺激疗效分析

发布时间：2018-02-17 01:19

本文关键词： 低频重复经颅磁刺激(r TMS) 急性脑梗死疗效　出处：《中国公共卫生》2017年07期 　论文类型：期刊论文

【摘要】：目的分析低频重复经颅磁刺激(rTMS)对急性脑梗死患者的疗效,为急性脑梗死的治疗提供科学依据。方法整群抽取2016年1—11月在河北承德医学院附属医院接受治疗的200例急性脑梗死伴有偏瘫患者,将其随机分为rTMS组和常规组各100例,2组均给予常规康复治疗,rTMS组同时给予rTMS治疗,比较2组患者的美国国立卫生研究院卒中量表(NIHSS)评分、巴氏指数(BI)、Fugl-Meyer评分、运动诱发电位(MEP)潜伏期、MEP波幅、中枢运动传导时间(CMCT)和汉密尔顿焦虑量表(HAMA)评分等指标,以评价rTMS对急性脑梗死患者的疗效。结果rTMS组与常规组患者治疗前比较,2组患者NIHSS评分、BI指数、Fugl-Meyer评分、MEP潜伏期、MEP波幅、CMCT、HAMA评分等指标差异均无统计学意义(均P0.05);治疗2周后,rTMS组患者的BI指数[(69.43±7.85)%]、Fugl-Meyer评分[(65.20±6.84)分]和MEP波幅[(1.04±0.19)mv]均高于常规组患者的[(63.18±8.40)%]、[(60.88±7.47)分]和[(0.91±0.15)mv],NIHSS评分[(5.13±1.96)分]、MEP潜伏期[(23.72±0.43)ms]和CMCT[(10.11±0.49)ms]均低于常规组患者的[(5.72±1.88)分]、[(24.10±0.38)ms]和[(10.67±0.43)ms],差异均有统计学意义(均P0.05);治疗4周后,rTMS组患者的BI指数[(83.20±8.17)%]、Fugl-Meyer评分[(74.12±6.65)分]和MEP波幅[(1.15±0.16)mv]均高于常规组患者的[(76.94±9.35)%]、[(69.36±7.17)分]和[(0.96±0.18)mv],NIHSS评分[(3.27±1.05)分]、MEP潜伏期[(23.12±0.36)ms]、CMCT[(9.62±0.51)ms]和HAMA评分[(7.53±1.86)分]均低于常规组患者的[(4.06±1.13)分]、[(23.70±0.47)ms]、[(10.01±0.64)ms]和[(8.96±1.97)分],差异均有统计学意义(均P0.05)。结论rTMS可明显改善急性脑梗死患者的运动功能及焦虑状态。
[Abstract]:Objective to analyze the effect of low frequency repetitive transcranial magnetic stimulation (RTMS) on patients with acute cerebral infarction. Methods 200 patients with acute cerebral infarction with hemiplegia were selected from 2016 to November in affiliated Hospital of Chengde Medical College of Hebei Province. They were randomly divided into two groups: rTMS group and routine group (n = 100). Both groups were given routine rehabilitation therapy and rTMS treatment. The NIHSS scores of the two groups were compared, and the Pap index Fugl-Meyer score was compared between the two groups. The latent period of motor evoked potential (MEP), the amplitude of MEP, the central motor conduction time (CMCTs) and the Hamilton anxiety scale (Hama) score, etc. Results there was no significant difference in NIHSS score and Fugl-Meyer score between rTMS group and routine group before treatment, and there was no significant difference in NIHSS latency and amplitude of MEP wave and Hama score between rTMS group and control group (P 0.05). The BI index [69.43 卤7.85mv] Fugl-Meyer score [65.20 卤6.84] and the amplitude of MEP (1.04 卤0.19mv) in the rTMS group were significantly higher than those in the normal group [63.18 卤8.40%], [60.88 卤7.47] and [0.91 卤0.15mv] [5.13 卤1.96] and the latency of MEP [23.72 卤0.43ms] and CMCT [10.11 卤0.491ms] were significantly lower than those in the normal group [63.18 卤8.40%] and [0.91 卤0.15mv] [5.13 卤1.96], respectively. There was significant difference in the latency of MEP [23.72 卤0.43 Ms] and CMCT [10.11 卤0.49 Ms]. The BI index [83.20 卤8.17g%] Fugl-Meyer score [74.12 卤6.65] and the MEP amplitude [1.15 卤0.16mv] in the rTMS group [76.94 卤9.35%], [69.36 卤7.17) minutes] and [0.96 卤0.18mv] NIHSS score [3.27 卤1.05m] in the control group were significantly lower than those in the routine group [23.12 卤0.36ms] and HAMA scores [9.62 卤0.51ms] and 0.64ms 卤0.64ms (7.53 卤1.86mv). [0.96 卤0.18mv] [3.27 卤1.05mV] [23.12 卤0.36ms] and HAMA scores [7.53 卤1.86ms] were significantly lower than those in the routine group [76.94 卤9.35mv] and [0.96 卤0.18mv] [3.27 卤1.05m] and [23.12 卤0.36ms] and HAMA scores (7.53 卤1.86ms), respectively. The difference was statistically significant (P 0.05). Conclusion rTMS can significantly improve motor function and anxiety state in patients with acute cerebral infarction.
【作者单位】：承德医学院附属医院老年病科;
【分类号】：R743.33

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