疏血通注射液对急性心肌梗死患者相关指标的影响

发布时间：2018-03-15 04:22

本文选题：疏血通注射液　切入点：尿激酶　出处：《中国药房》2017年24期 　论文类型：期刊论文

【摘要】：目的:探讨疏血通注射液对急性心肌梗死(AMI)患者相关指标的影响。方法 :回顾性分析156例AMI患者资料,按治疗方案的不同分为对照组(65例)和观察组(91例)。对照组患者给予常规治疗;观察组患者在对照组治疗的基础上给予疏血通注射液6 mL,加入5%葡萄糖注射液250 mL中,静脉滴注,每日1次。两组均连续治疗5 d。观察两组患者的血管再通率、再通时间、再闭塞发生率,治疗前后左心室射血分数(LVEF)、活化部分凝血酶原时间(APTT)、凝血酶原时间(PT)、纤维蛋白原(FIB)水平,不良心血管事件发生情况及不良反应发生情况。结果:观察组患者血管再闭塞发生率、不良心血管事件总发生率均显著低于对照组,差异均有统计学意义(P0.05);两组患者血管再通率、再通时间、不良反应发生率比较,差异均无统计学意义(P0.05)。治疗后,两组患者LVEF、APTT、PT均显著高于同组治疗前,且观察组显著高于对照组;两组患者FIB显著低于同组治疗前,且观察组显著低于对照组,差异均有统计学意义(P0.05)。结论 :在常规治疗的基础上,疏血通注射液可降低AMI患者的血管再闭塞发生率,改善心功能,减少不良心血管事件发生,且未增加不良反应的发生。
[Abstract]:Objective: to investigate the effect of Shuxuetong injection on the related indexes in patients with acute myocardial infarction (AMI). Methods: the data of 156 patients with AMI were analyzed retrospectively. The patients in the observation group were given routine treatment, and the patients in the observation group were given Shuxuetong injection 6 mL on the basis of the treatment in the control group, which was added to 5% glucose injection 250ml, and the control group was divided into two groups: the control group (n = 65) and the observation group (n = 91). Two groups were treated continuously for 5 days. The rate of recanalization, the time of recanalization and the incidence of re-occlusion were observed. Before and after treatment, left ventricular ejection fraction (LVEF), activated partial prothrombin time (APTTT), prothrombin time (PTT), fibrinogen (FIBs), adverse cardiovascular events and adverse reactions were observed. The total incidence of adverse cardiovascular events was significantly lower than that of the control group (P 0.05), and there was no significant difference between the two groups in vascular recanalization rate, recanalization time and adverse reaction rate. The FIB of the two groups was significantly lower than that of the control group, and the FIB of the observation group was significantly lower than that of the control group, and that of the observation group was significantly lower than that of the control group. Conclusion: Shuxuetong injection can reduce the incidence of vascular re-occlusion, improve cardiac function, reduce adverse cardiovascular events, and do not increase the incidence of adverse reactions on the basis of routine treatment.
【作者单位】：重庆市璧山区人民医院心血管内科;
【分类号】：R542.22

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