重型颅脑外伤患者术后医院感染的病原学分析

发布时间：2018-03-23 20:32

  本文选题：重型颅脑外伤　切入点：感染　出处：《中华医院感染学杂志》2016年07期

【摘要】：目的探讨神经外科重型脑外伤患者术后感染、病原菌及耐药性,并分析控制术后感染的对策,以减少多重感染。方法选取医院2006-2013年重型脑外伤手术患者219例,对发生感染的患者留取标本进行病原菌培养和鉴定,数据采用WHONET 5.4软件进行统计分析。结果 2006-2013年重型颅脑外伤手术患者219例,其中发生感染69例,感染率31.51%;69例感染患者共培养出257株病原菌,以革兰阴性菌为主,共195株占75.88%;主要革兰阴性菌对亚胺培南和头孢哌酮/舒巴坦的耐药率较低,均20.00%。结论神经外科重型脑外伤术后患者医院感染的发生率较高,多为多药耐药菌感染,临床应采取措施控制感染的发生,发现患者有感染,应立即分离培养病原菌及耐药试验,后给予针对性治疗,避免发生多重感染。
[Abstract]:Objective to investigate postoperative infection, pathogenic bacteria and drug resistance in patients with severe brain trauma in neurosurgery, and to analyze the countermeasures to control postoperative infection in order to reduce multiple infections. Methods 219 patients with severe brain trauma in hospital from 2006 to 2013 were selected. The pathogens were cultured and identified in the specimens collected from the infected patients. The data were analyzed by WHONET 5.4 software. Results from 2006 to 2013, there were 219 patients with severe craniocerebral trauma, 69 of whom were infected. 257 strains of pathogenic bacteria were cultured in 69 patients with infection rate of 31.51%, among which 195 strains were Gram-negative bacteria (75.88%), and the resistance rate of the main gram-negative bacteria to imipenem and cefoperazone / sulbactam was low, and the rate of resistance to imipenem and cefoperazone / sulbactam was lower. Conclusion the incidence of nosocomial infection in patients with severe brain trauma after neurosurgery is higher, most of them are multidrug resistant bacteria infection. Clinical measures should be taken to control the occurrence of infection. After the targeted treatment, to avoid multiple infections.
【作者单位】： 江山市人民医院神经外科;江山市人民医院呼吸内科;江山市人民医院院感科;
【基金】：浙江省医药卫生科技基金资助项目(2011KYA166)
【分类号】：R651.15;R197.323
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本文编号：1655074