血必净注射液对老年脓毒症患者心肌损伤的保护作用

发布时间：2018-03-26 00:14

本文选题：血必净注射液　切入点：脓毒症　出处：《中国老年学杂志》2017年19期

【摘要】：目的探讨血必净注射液对老年脓毒症患者心肌损伤的保护作用。方法选择老年脓毒症心肌损伤患者,随机分为对照组和治疗组,两组均给予常规集束化治疗,治疗组另外给予血必净注射液。治疗前、治疗后5、10 d,抽取静脉血检测肌钙蛋白I(c Tn I)、肌酸激酶同工酶(CKMB)、降钙素原(PCT)、C反应蛋白(CRP)水平。记录两组ICU住院时间、28 d病死率。结果治疗后5、10 d,两组c Tn I、CK-MB、PCT、CRP均明显下降(P0.05),且治疗组均明显低于对照组(P0.05)。治疗组ICU住院时间明显短于对照组(P0.05)。治疗组28 d病死率低于对照组,差异无统计学意义(P0.05)。结论血必净注射液可以改善老年脓毒症心肌损伤患者的c Tn I、CK-MB、PCT、CRP水平,对心肌损伤具有保护作用。
[Abstract]:Objective to investigate the protective effect of Xuebijing injection on myocardial injury in elderly patients with sepsis. Methods aged patients with sepsis were randomly divided into control group and treatment group. The treatment group was given Xuebijing injection in addition. Before treatment, The levels of cTnTnI, creatine kinase isoenzyme (CKMBN) and procalcitonin (ICU) were measured at 5 and 10 days after treatment. The fatality rate of ICU in both groups was recorded for 28 days. Results after 5 to 10 days of treatment, the levels of CRP in both groups were significantly higher than those in the control group. The ICU hospitalization time of the treatment group was significantly shorter than that of the control group (P 0.05). The fatality rate of the treatment group was lower than that of the control group at 28 days. Conclusion Xuebijing injection can improve the level of CRP in elderly patients with myocardial injury of sepsis and has protective effect on myocardial injury.
【作者单位】：唐山市第二医院ICU;唐山市第二医院骨科;唐山市第二医院检验科;唐山市人民医院ICU;
【基金】：河北省医学科学研究重点课题(No.ZD20140379)
【分类号】：R459.7

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