ASS评分、C-反应蛋白及白细胞变化在脑外伤患者早期感染中的监测价值

发布时间：2018-03-31 19:05

  本文选题：脑外伤　切入点：应激反应　出处：《中华医院感染学杂志》2017年02期

【摘要】：目的探讨全身炎症反应综合征修正(ASS)评分、C-反应蛋白及白细胞监测鉴别脑外伤患者应激反应与早期感染的临床价值。方法选取2014年3月-2015年3月收治的脑外伤患者72例,按是否发生早期感染分为非感染组与感染组,每组36例,两组患者均在入院1周内进行ASS评分,同时分别于入院1、3、5、7、10、14、21d测定患者C-反应蛋白、外周血白细胞计数(WBC)水平,并记录其体温变化。结果感染组ASS评分(8.85±2.37)分,显著高于非感染组的(4.01±1.22)分,差异有统计学意义(t=3.7738,P0.05),非感染组C-反应蛋白水平无明显变化;感染组入院1、3、5、7dC-反应蛋白水平显著高于非感染组,差异有统计学意义(P0.05);感染组入院1、3、5dWBC计数水平与非感染组接近,但感染组入院7d后WBC水平明显升高,直至第10天达到峰值,随后开始逐渐下降,感染组入院1、3、5、7、10、14、21d WBC水平均高于非感染组(P0.05);感染组入院当日均有发热症状,平均体温(38.4±1.3)℃,经治疗后,两组患者体温均出现下降,感染组在入院第7天体温有所升高,直至第10天达到峰值后逐渐下降,与感染组相比,非感染组5d后体温小幅度变化。结论脑外伤患者入院后的C-反应蛋白、外周血WBC计数及体温变化趋势对早期感染的诊断有指示意义,而ASS评分对早期感染有良好的预测价值,有利于脑外伤早期感染的鉴别诊断。
[Abstract]:Objective to investigate the clinical value of C-reactive protein (CRP) and leukocyte monitoring in differentiating stress reaction from early infection in patients with traumatic brain injury.Methods from March 2014 to March 2015, 72 patients with traumatic brain injury were selected and divided into two groups according to whether early infection occurred. There were 36 cases in each group. The patients in both groups were assessed with ASS within one week of admission.At the same time, the level of C-reactive protein (CRP) and white blood cell count (WBC-) were measured on the 21st day after admission, and their body temperature was recorded.The level of WBC in the infected group was close to that in the non-infected group, but the level of WBC in the infected group increased obviously 7 days after admission, reached its peak value on the 10th day, and then decreased gradually.The WBC level in the infection group was higher than that in the non-infection group on the 21st day after admission, and the fever symptom was found in the infection group on the admission day, the average body temperature was 38.4 卤1.3 鈩，

本文编号：1692039