spontaneous intracerebral hemorrhage hematoma further expand

  本文关键词：自发性脑出血急性期血肿扩大相关危险因素，由笔耕文化传播整理发布。

自发性脑出血急性期血肿扩大相关危险因素

Risk factors of hematoma enlargement in spontaneous intracerebral hemorrhage at acute stage

[1] [2] [3] [4]

WU Yan;REN Ming-shan;CHENG Zhao-zhao;（Department of neurology,Affiliated provincial hospital of anhui medical university; Hefei 230001, China）

安徽医科大学附属省立医院神经内科,合肥230000

文章摘要：目的探讨自发性脑出血急性期血肿扩大的相关危险因素。方法收集97例自发性脑出血患者的临床资料。于发病6 h及48 h时对患者进行头颅CT检查。分析血肿扩大的相关危险因素。结果根据5点分级标准,规则血肿48例（49.48%）,不规则血肿49例（50.52%）;均质血肿62例（63.92%）,不均质血肿35例（36.08%）。27例（27.84%）患者发生血肿扩大（血肿扩大组）,70例（72.16%）患者血肿无进展（血肿未扩大组）。与血肿未扩大组比较,血肿扩大组患者年龄、血肿量、入院时及入院3 h的收缩压,以及高血压病、糖尿病、抗凝治疗史、吸烟史、不规则血肿、不均质血肿的比率均显著增高,GCS显著降低（P〈0.05∽0.01）。多因素Logistic分析发现,不均质血肿和入院3 h收缩压升高是血肿扩大的独立危险因素（OR=47.377,95%CI：7.827∽286.789,P〈0.001;OR=20.969,95%CI：3.826∽114.923,P〈0.001）。结论不均质血肿和入院3 h SBP升高是血肿扩大的独立危险因素。

Abstr：Objective To investigate the risk factors of hematoma enlargement in spontaneous intracerebral hemorrhage at acute stage. Methods The clinical data of 97 spontaneous intracerebral hemorrhage patients were collected. The brain CT was checked at 6 h and 48 h after noset. The related risk factors of hematoma enlargement were analyzed. Results According to 5-point categorical scales,regular hematomata was in 48 cases（ 49. 48%）,and irregular hematomata was in 49 caese（ 50. 52%）; homogeneous hematomata was in 62 cases（ 63. 92%）,and heterogeneous hematomata was in 35 cases（ 36. 08%）. Twenty-seven cases（ 27. 84%） had hematoma enlargement（ hematoma enlargement group）,and 70 cases（ 72. 16%） didn＇t have hematoma enlargement（ no-hematoma enlargement group）. Compared with no-hematoma enlargement group,age,hematoma volume,systolic pressure at admission and 3 h after admission,and the rates of hypertension,diabetic,anticoagulant treatment history,smoke,irregular hematomata,heterogeneous hematomata in hematoma enlargement group were significantly increased,GCS was significantly decreased（ P〈0. 05- 0. 01）. Multivariate Logistic analysis showed heterogeneous hematomata and systolic pressure at 3 h after admission were independent risk factors of hematoma enlargement（ OR = 47. 377,95%CI： 7. 827- 286. 789,P〈0. 001; OR = 20. 969,95% CI： 3. 826- 114. 923,P〈0. 001）. Conclusion Heterogeneous hematomata and systolic pressure at 3 h after admission are independent risk factors of hematoma enlargement.

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Keyword：:spontaneous intracerebral hemorrhage hematoma further expand risk factors

课题项目：安徽省卫生厅科研课题（13ZC016）

作者信息：会员可见

  本文关键词：自发性脑出血急性期血肿扩大相关危险因素，由笔耕文化传播整理发布。