经抽吸导管冠脉闭塞段内注入替罗非班治疗急性心肌梗死

发布时间：2018-04-13 22:13

  本文选题：急性心肌梗死 + 血栓抽吸导管　； 参考：《实用医学杂志》2016年18期

【摘要】：目的:研究经抽吸导管在冠状动脉闭塞段内注入替罗非班对冠脉开通时间、开通后血流改善情况及患者近30 d不良事件发生率的影响。方法:我院近4年收住的97例经冠脉造影证实罪犯血管为次全闭塞或完全闭塞的急性心肌梗死患者,随机分为血栓抽吸组(A组)、闭塞段注入替罗非班+血栓抽吸组(B组)。比较两组冠脉开通时间、开通后血流改善情况及患者近30 d不良事件发生率的影响。结果:A组冠脉开通时间较B组缩短(P0.05);B组血流达到TIMIⅢ级时间较A组缩短(P0.05);B组早期无复流发生率较A组低,早期血流达TIMIⅢ级比例较A组提高(P0.05);B组较A组30 d患者不良事件发生率下降,但差异无统计学意义(P0.05)。结论:替罗非班在冠脉闭塞段直接注入可有效降低血管开通时间及早期无复流现象的发生率,改善冠脉灌注,不能降低30 d患者不良心血管事件发生率。
[Abstract]:Objective: to study the effects of injecting tirofiban into the occlusive segment of coronary artery via suction catheter on the duration of coronary artery opening, the improvement of blood flow and the incidence of adverse events in patients with coronary artery occlusion in the past 30 days.Methods: 97 patients with acute myocardial infarction (AMI) who were confirmed by coronary angiography to be subtotal occlusion or total occlusion were randomly divided into thrombotic aspiration group (group A) and tirofiban thrombotic aspiration group (group B).The time of coronary artery opening, the improvement of blood flow and the incidence of adverse events in 30 days were compared between the two groups.Results the duration of coronary artery opening in group A was shorter than that in group B (P 0.05). The time of blood flow to TIMI 鈪，

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