老年急性缺血性脑卒中4.5 h后Solitarie支架取栓与动脉溶栓疗效比较

发布时间：2018-04-24 10:35

本文选题：缺血性脑卒中 + Solitarie支架　；参考：《中国老年学杂志》2017年07期

【摘要】：目的探讨老年急性缺血性脑卒中4.5 h后Solitarie支架取栓与动脉溶栓疗效比较。方法选择发病4.5 h后老年急性缺血性脑卒中行Solitarie支架取栓患者50例作为取栓组、动脉溶栓患者50例作为溶栓组。比较两组患者治疗前后美国国立卫生院卒中量表(NIHSS)评分、再通时间及再通率、并发症情况。结果取栓组术前NIHSS评分和溶栓组比较差异无统计学意义(P0.05),取栓组术后2 h、24 h NIHSS评分显著低于溶栓组(P0.05),取栓组术后14 d和术后90 d NIHSS评分和溶栓组比较差异无统计学意义(P0.05);两组术后2 h、24 h、14 d、90 d NIHSS评分均低于术前(P0.05)。取栓组再通时间显著短于溶栓组(P0.05);取栓组完全再通36例,部分再通8例,未通6例,共44例再通,再通率88.0%,溶栓组完全再通23例,部分再通6例,未通21例,共29例再通,再通率58.0%,取栓组治疗后再通率显著高于溶栓组(P0.05)。取栓组再闭塞率、再出血率、死亡率和溶栓组比较差异均无统计学意义(P0.05)。结论老年急性缺血性脑卒中4.5 h后行Solitarie支架取栓治疗安全有效,血管再通率高,能够延长脑卒中的治疗"时间窗"。
[Abstract]:Objective to compare the effect of Solitarie stent thrombolysis and arterial thrombolysis in elderly patients with acute ischemic stroke after 4.5 h. Methods 50 patients with acute ischemic stroke after 4.5 h were selected as thrombolytic group and 50 patients with thrombolytic thrombolysis were used as thrombolytic group. The national health hospital died before and after the treatment of the two groups. There was no significant difference between NIHSS score and thrombolytic group before operation (P0.05), 2 h after operation in thrombolytic group and 24 h NIHSS score in thrombolytic group were significantly lower than that in thrombolytic group (P0.05). There was no significant difference between 14 d and 90 d NIHSS scores after operation in thrombolytic group and thrombolytic group (P0). .05); two groups of 2 h, 24 h, 14 d, 90 d NIHSS scores were lower than before the operation (P0.05). The repass time of the thrombolytic group was significantly shorter than the thrombolytic group (P0.05); the thrombolytic group was completely repassed in 36 cases, 8 cases were repassed, and 6 cases were repassed, the repass rate was 88%, the thrombolytic group was completely repassed 23 cases, some 6 cases were repassed without 21 cases, a total of 29 cases repass, repass rate, embolus The rate of repassage after treatment was significantly higher than that in thrombolytic group (P0.05). There was no significant difference in reocclusion rate, rebleeding rate, mortality rate and thrombolytic group (P0.05). Conclusion Solitarie stent embolectomy after 4.5 h for elderly patients with acute ischemic stroke was safe and effective, and the rate of vascular repassage was high, which could prolong the treatment "time window" of stroke.

【作者单位】：宿州市第一人民医院脑血管病诊疗中心;
【分类号】：R743.3

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