nCPAP干预治疗对非急性期脑梗死合并OSAHS患者神经功能的影响

发布时间：2018-04-26 03:25

本文选题：持续气道正压通气 + 脑梗死　；参考：《重庆医学》2016年06期

【摘要】：目的探讨经鼻持续气道正压通气(nCPAP)干预治疗对非急性期脑梗死(CI)合并阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者神经功能的影响。方法 68例患者经头颅CT或MRI确诊为CI且处于非急性期后,经多导睡眠图(PSG)诊断为OSAHS,将其分为观察组和对照组,对照组给予神经内科常规治疗,观察组在对照组基础上给予每晚大于4h的nCPAP呼吸机治疗,分别于治疗后1、3、6个月时根据美国国立卫生研究院卒中量表(NIHSS)对患者进行神经功能评分,爱泼沃斯嗜睡量表(ESS)进行嗜睡评分及用标准吞咽功能评定量表(SSA)进行吞咽功能评分。结果 nCPAP呼吸机治疗的观察组ESS评分下降,NIHSS评分上升,与对照组比较差异有统计学意义(P0.05);而SSA评分与对照组比较差异无统计学意义(P0.05)。结论nCPAP治疗可有效改善非急性期CI合并OSAHS患者症状,使其神经功能恢复,是临床一种药物以外的有效方法。
[Abstract]:Objective to investigate the effect of nasal continuous positive airway pressure (CPAP) intervention on neurologic function in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) after non-acute cerebral infarction (CI). Methods 68 patients with CI diagnosed by CT or MRI were diagnosed as OSAHS by polysomnography (PSG). They were divided into observation group and control group. The observation group was treated with nCPAP ventilator for more than 4 hours per night on the basis of the control group. The patients were assessed according to the National Institutes of Health Stroke scale (NIHSS) at 1 and 6 months after treatment. Epworth sleepiness scale (ESS) and standard swallowing function scale (SSAs) were used to evaluate somnolence. Results the ESS score of the nCPAP ventilator group decreased and the NIHSS score increased, which was significantly higher than that of the control group (P 0.05), but the SSA score was not significantly different from that of the control group (P 0.05). Conclusion nCPAP treatment can effectively improve the symptoms of CI patients with OSAHS in non-acute stage and restore their neurological function. It is an effective method in addition to clinical drugs.
【作者单位】：广东医学院第二附属医院呼吸内科;
【基金】：2013年湛江市财政资金科技专项竞争性分配项目(2013A01017)
【分类号】：R743.3;R766

【相似文献】