腹腔镜胆囊切除术治疗急性结石性胆囊炎合并胆汁性腹膜炎的效果分析

发布时间：2018-05-05 11:19

本文选题：腹腔镜 + 急性结石性胆囊炎　；参考：《中华医院感染学杂志》2017年24期

【摘要】：目的探讨腹腔镜胆囊切除术治疗急性结石性胆囊炎合并胆汁性腹膜炎的术后感染效果。方法回顾性分析2015年1月-2017年1月于医院行急性结石性胆囊炎合并胆汁性腹膜炎手术的63例患者的资料,按照患者的手术方法分组,利用开腹方法进行手术的为对照组28例,利用腹腔镜介导的方法进行手术的为试验组35例,观察分析两组患者的治疗效果。结果试验组的手术出血量与手术后3d的疼痛评分均低于对照组(P0.05);采用重复测量数据的方差分析显示,对照组与试验组在手术前,手术后1、3、5、7d的体温、白细胞计数(WBC)、C-反应蛋白(CRP)、白细胞介素-6(IL-6),降钙素(PCT)、肿瘤坏死因子-α(TNF-α)和红细胞沉降率(ESR)比较,在不同时间点均差异有统计学意义,且试验组均低于对照组(P0.05);对照组与试验组的数据处理因素与时间之间均存在交互作用(P0.05)。结论利用腹腔镜胆囊切除术治疗急性结石性胆囊炎合并胆汁性腹膜炎的患者,可以降低患者手术后感染的风险。
[Abstract]:Objective to evaluate the effect of laparoscopic cholecystectomy (LC) on postoperative infection of acute calculous cholecystitis complicated with biliary peritonitis. Methods the data of 63 patients with acute calculous cholecystitis complicated with biliary peritonitis from January 2015 to January 2017 were analyzed retrospectively. The treatment effect of the two groups was observed and analyzed by laparoscopically mediated operation in 35 patients in the experimental group. Results the amount of operative bleeding and the pain score 3 days after operation in the trial group were lower than those in the control group (P 0.05), and the body temperature of the control group and the experimental group was 1: 3 and 5 days after operation before and after operation by means of variance analysis of repeated measurement data. The WBC count and erythrocyte sedimentation rate (ESRR) were significantly different from those of CRP, IL-6, PCT, TNF- 伪 and ESRs at different time points. The data processing factors and time of the control group and the control group were all lower than that of the control group, and the interaction between the data processing factors of the control group and the experimental group was P0.05. Conclusion Laparoscopic cholecystectomy can reduce the risk of postoperative infection in patients with acute calculous cholecystitis complicated with biliary peritonitis.
【作者单位】：宁波市第二医院肝胆胰外科;
【基金】：浙江省自然科学基金资助项目(Y2080096)
【分类号】：R657.4

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