吸烟对不同性别、年龄人群急性ST段抬高型心肌梗死发病风险的相关性研究

发布时间：2018-05-09 02:11

  本文选题：心肌梗死 + 吸烟　； 参考：《中国循环杂志》2016年09期

【摘要】：目的:探讨吸烟对不同性别、年龄人群急性ST段抬高型心肌梗死(STEMI)的致病风险是否存在差异。方法:采用病例对照研究设计(1:1匹配),入选我院2010-01-14至2016-01-27连续收治的2 026例明确诊断为STEMI的患者和2 026例按性别、年龄(±2岁)匹配的同期入院行健康体检或择期外科手术的对照人群,进行吸烟与STEMI发病风险的相关性分析。结果:吸烟是男性STEMI的重要危险因素,且与年龄呈负相关:吸烟患STEMI的青年男性(≤45岁)调整比值比(OR)=7.000[95%可信区间(CI):4.235~11.570],中年男性(46~59岁)调整OR=5.296(95%CI:3.904~7.185),老年男性(≥60岁)调整OR=4.686(95%CI:2.860~4.751)。结论:吸烟是STEMI的主要危险因素,但其相对致病风险度存在年龄和性别差异,对青年男性的相对致病风险最高且是最主要的致病因素。
[Abstract]:Objective: to investigate whether smoking affects the risk of STEMIs in patients with acute ST-segment elevation myocardial infarction (STEMI) in different sex and age groups. Methods: a case-control study was carried out to select 2 026 patients with STEMI and 20 026 patients by sex who were admitted to our hospital from 2010-01-14 to 2016-01-27. The correlation between smoking and risk of STEMI was analyzed in matched control population with age (卤2 years) who were hospitalized for physical examination or elective surgery at the same time. Results: smoking was an important risk factor for male STEMI, and it was negatively correlated with age: the adjusted ratio of young men (鈮，

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