负压封闭引流术治疗慢性难愈性创面的回顾性分析

发布时间：2018-05-19 19:13

本文选题：负压封闭引流 + 慢性难愈性创面　；参考：《南昌大学》2017年硕士论文

【摘要】：目的:本研究通过回顾性分析负压封闭引流技术治疗压力性溃疡创面、糖尿病溃疡创面患者的资料,探讨负压封闭引流治疗难愈性创面的效果方法:对166例慢性难愈性创面患者(其中压力性溃疡创面患者118例,糖尿病溃疡创面48例)的临床资料进行回顾性分析。根据两组资料中患者在治疗过程中是否使用负压封闭引流技术再分为VSD治疗组和对照组,对患者从入院至满足条件行二期手术(局部皮瓣转移术或植皮术)的时间和手术封闭创面后患者创面的愈合效果做出统计学分析。结果:1、压力性溃疡创面治疗过程中,VSD治疗组从入院至满足条件行二期手术所需时间为12.89±7.064天;对照组从入院至满足条件行二期手术所需时间为为19.83±10.897天。经两独立样本T检验,t=-3.892,P0.01,具有显著的统计学意义。2、压力性溃疡创面治疗过程中,行手术治疗封闭创面2周后,VSD治疗组中有48例痊愈,16例显效,6例无效,治愈率为68.57%;对照组中有28例痊愈,10例显效,10例无效,治愈率为58.33%。经Wilcoxon秩和检验,P0.01,具有统计学意义。3、糖尿病溃疡创面治疗过程中,VSD治疗组从入院至满足条件行二期手术所需时间为10.90±6.226天;对照组从入院至满足条件行二期手术所需时间为18.53±5.433天。经T检验,t=-4.413,P0.01,具有的统计学意义。4、糖尿病溃疡创面治疗过程中,行二期手术2周后,VSD治疗组中有24例痊愈,4例显效,3例无效,治愈率为77.45%;对照组中有9例痊愈,5例显效,3例无效,治愈率为52.94%。经Wilcoxon秩和检验,P0.01,具有显著统计学意义。结论:负压封闭引流技术能加快创面肉芽生长速度,显著的缩短患者从入院至行二期手术封闭创面所需的时间。且对比于传统的清创换药治疗方法比,行负压封闭引流术联合皮瓣或植皮术治疗慢性难愈性创面的效果显著提高。负压封闭引流技术是治疗慢性难愈性创面的一种简单、有效的方法。
[Abstract]:Objective: to retrospectively analyze the data of patients with pressure ulcer and diabetic ulcer treated by negative pressure sealing drainage. Methods: the clinical data of 166 patients with chronic refractory wounds (including 118 patients with pressure ulcer and 48 patients with diabetic ulcer) were analyzed retrospectively. According to the data of the two groups, the patients were divided into two groups: VSD treatment group and control group. The time of secondary operation (local flap transfer or skin grafting) from admission to condition was analyzed statistically. Results in the treatment of stress ulcer wounds, the time of secondary operation was 12.89 卤7.064 days in the VSD group and 19.83 卤10.897 days in the control group. After two independent T tests, there was significant statistical significance. During the treatment of pressure ulcer wounds, 48 cases were cured and 6 cases were ineffective in VSD treatment group after 2 weeks of operation. The cure rate was 68.57 and the cure rate was 58.33 in the control group. After Wilcoxon rank sum test (P 0.01), there was statistical significance. During the treatment of diabetic ulcer wound, the time from admission to condition was 10.90 卤6.226 days in the treatment group and 18.53 卤5.433 days from admission to condition in the control group. In the treatment of diabetic ulcer wounds, 24 cases were cured 2 weeks later in VSD treatment group, 4 cases were cured, 3 cases were ineffective, the cure rate was 77.45%, in the control group, 9 cases were cured, 5 cases had obvious effect and 3 cases had no effect. The cure rate was 52.94. Wilcoxon rank sum test showed significant statistical significance (P 0.01). Conclusion: the technique of negative pressure sealing and drainage can accelerate the growth rate of granulation and shorten the time of wound sealing from admission to secondary operation. Compared with the traditional methods of debridement and dressing replacement, the effect of negative pressure sealing drainage combined with skin flap or skin grafting on chronic refractory wounds was significantly improved. Negative pressure sealing and drainage is a simple and effective method for the treatment of chronic refractory wounds.
【学位授予单位】：南昌大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R641

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