经皮经肝胆囊穿刺引流术联合腹腔镜胆囊切除术治疗急性危重胆囊炎的短期疗效及对患者免疫功能的影响

发布时间：2018-06-05 19:57

本文选题：经皮经肝胆囊穿刺引流术 + 腹腔镜胆囊切除术　；参考：《中国老年学杂志》2017年23期

【摘要】：目的探讨经皮经肝胆囊穿刺引流术(PTGBD)联合腹腔镜胆囊切除术(LC)治疗急性危重胆囊炎的短期疗效及对患者免疫功能的影响。方法回顾性分析2014年8月至2016年8月该院接收的95例急性危重胆囊炎患者的临床资料,其中接受LC治疗的对照组患者52例,接受PTGBD联合LC的观察组43例,比较两组短期疗效指标、免疫功能指标和免疫球蛋白指标。结果观察组术中出血量、术后腹腔引流时间、术后经口进食时间显著优于对照组(均P0.05);术后1、8 d两组CD3~+、CD4~+、CD4~+/CD8~+活性无统计学差异(P0.05);术后1、8 d两组免疫球蛋白水平比较无统计学意义(P0.05)。结论PTGBD联合LC治疗急性危重胆囊炎短期疗效好,对患者免疫功能影响较小。
[Abstract]:Objective to investigate the short-term effect of percutaneous transhepatic cholecystectomy (PTGBD) combined with laparoscopic cholecystectomy (LC) on acute severe cholecystitis and its effect on immune function. Methods the clinical data of 95 patients with acute severe cholecystitis received from August 2014 to August 2016 were retrospectively analyzed. Among them, 52 cases were treated with LC and 43 cases were treated with PTGBD combined with LC. The short-term curative effect index, immune function index and immunoglobulin index were compared between the two groups. Results the amount of intraoperative bleeding and the time of postoperative abdominal drainage were observed in the observation group. The oral feeding time was significantly better than that of the control group (all P 0.05), and there was no significant difference in the activity of CD3 ~ + CD _ 4 ~ + CD _ 4 ~ / CD _ 8 ~ C between the two groups on the 8th day after operation (P 0.05), but there was no significant difference in the level of immunoglobulin between the two groups on the 1st and 8th day after operation (P 0.05). Conclusion PTGBD combined with LC is effective in the treatment of acute severe cholecystitis and has little effect on immune function.
【作者单位】：海西州人民医院普外科;
【分类号】：R657.41

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