早期小剂量糖皮质激素对脓毒症休克患者血流动力学及预后的影响

发布时间：2018-06-05 22:48

本文选题：脓毒症 + 休克　；参考：《中西医结合心血管病电子杂志》2017年25期

【摘要】：目的探讨早期应用小剂量糖皮质激素对脓毒症休克患者血流动力学及预后的影响。方法将2015年2月~2017年2月于我院接受治疗的53例脓毒症休克患者作为研究对象,将患者分为对照组、早治疗组、晚治疗组,分析患者的血流动力学及预后情况。结果早治疗组患者在治疗12 h、24 h、48 h后的平均动脉压均明显高于其他两组,组间对比差异有统计学意义(P0.05);在心率方面,早治疗组在治疗12 h、24 h、48 h时显著低于其他两组,且差异有统计学意义(P0.05)。此外在预后指标方面,早治疗组的机械通气时间、住ICU时间、住院时间等均明显短于其他两组,差异有统计学意义(P0.05)。结论临床上在治疗脓毒症休克患者时,可在常规治疗的基础上于早期采用小剂量糖皮质激素进行治疗,能够更快促进患者血流动力学的恢复,改善预后质量。
[Abstract]:Objective to investigate the effect of early application of low dose glucocorticoid on hemodynamics and prognosis of septic shock patients. Methods 53 patients with septic shock who were treated in our hospital from February 2015 to February 2017 were divided into control group, early treatment group and late treatment group. The hemodynamics and prognosis of the patients were analyzed. Results the mean arterial pressure in the early treatment group was significantly higher than that in the other two groups at 12 h, 24 h and 48 h after treatment, and the difference between the two groups was statistically significant (P 0.05), and the heart rate in the early treatment group was significantly lower than that in the other two groups at 12 h, 24 h and 48 h. The difference was statistically significant (P 0.05). In addition, the duration of mechanical ventilation, ICU stay and hospital stay in the early treatment group were significantly shorter than those in the other two groups, and the difference was statistically significant (P 0.05). Conclusion in clinical treatment of septic shock patients can be treated with low-dose glucocorticoid on the basis of routine therapy. It can accelerate hemodynamic recovery and improve the quality of prognosis.
【作者单位】：遵义市红花岗区人民医院;
【分类号】：R459.7

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