急性脑梗死患者血清脂联素与神经功能缺损程度的相关性

发布时间：2018-06-12 07:15

本文选题：脑梗死 + 血清脂联素　；参考：《广东医学》2017年S2期

【摘要】：目的研究血清脂联素(APN)水平与急性脑梗死患者神经功能缺损程度的相关性。方法测定55例急性脑梗死患者及51例健康对照者的APN、同型半胱氨酸(Hcy)、C反应蛋白(CRP),并分析治疗前、治疗3个月后APN水平与脑梗死患者神经功能缺损程度的相关性。结果脑梗死组与对照组治疗前、治疗3个月后APN比较差异有统计学意义(P0.05);Hcy治疗前后两组比较差异无统计学意义(P0.05);CRP治疗前后两组比较差异无统计学意义(P0.05)。APN降低、Hcy和CRP升高均是脑梗死的危险因素。治疗前APN与神经功能缺损程度呈负相关(r=-0.69,P0.01),治疗3个月后APN与神经功能缺损程度也呈负相关(r=-0.71,P0.01)。结论 APN水平与急性脑梗死神经功能缺损程度可能具有相关性。
[Abstract]:Objective to study the correlation between serum adiponectin (APN) level and neurological deficit in patients with acute cerebral infarction. Methods APN and homocysteine C reactive protein (HCH) C-reactive protein were measured in 55 patients with acute cerebral infarction (ACI) and 51 healthy controls. The correlation between APN levels and the degree of neurological impairment in patients with cerebral infarction was analyzed before and 3 months after treatment. Results before the treatment of cerebral infarction group and control group, There was significant difference in APN between the two groups after 3 months of treatment. There was no significant difference between the two groups before and after P0.05 Hcy treatment. There was no significant difference between the two groups before and after treatment. The decrease of Hcy and CRP were both risk factors of cerebral infarction. Before treatment, there was a negative correlation between APN and the degree of nerve function defect. After 3 months of treatment, there was a negative correlation between APN and the degree of nerve function defect. Conclusion APN level may be correlated with the degree of neurological deficit in acute cerebral infarction.
【作者单位】：重庆医科大学附属永川医院神经内科;
【基金】：重庆市永川区自然科学基金计划项目(编号:Ycstc,2014nc5021)
【分类号】：R743.33

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