hs-CRP、BNP和cTnI联合检测对急性心肌梗死患者PCI术后MACE的预测价值

发布时间：2018-06-16 14:27

本文选题：C反应蛋白质 + 肌钙蛋白I　；参考：《重庆医学》2017年03期

【摘要】：目的探讨急性心肌梗死患者经皮冠状动脉介入(PCI)治疗后超敏C反应蛋白(hs-CRP)、B型钠尿肽(BNP)、肌钙蛋白I(cTnI)联合检测对术后心脏不良事件(MACE)的预测价值。方法选取89例成功施行PCI术的初发AMI患者,PCI术前及术后采集血液标本,检测hs-CRP、BNP和cTnI水平。根据术后单项检测结果将患者分别分为hs-CRP高值组/hs-CRP低值组,BNP高值组/BNP低值组,cTnI高值组/cTnI低值组,根据联合检测结果将患者分为H1组(3项指标均非高值或仅有1项高值)、H2组(3项指标有2项为高值)和H3组(3项指标均为高值)组。比较各组之间MACE发生率。结果单项检查时,hsCRP、BNP和cTnI水平高值组MACE的发生率均高于低值组,差异有统计学意义(P0.01)。联合检测hs-CRP、BNP和cTnI水平,H1、H2及H3组MACE发生率比较差异有统计学意义(P0.01)。且H2组MACE发生率高于H1组,H3组MACE发生率高于H2组。结论 hs-CRP、BNP和cTnI水平与AMI患者PCI术后MACE的发生率密切相关,具有预测价值。
[Abstract]:Objective to investigate the predictive value of hypersensitive C-reactive protein (hs-CRP) B natriuretic peptide (BNPP) and cardiac troponin (I) cTnI in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI) for cardiac adverse events (MACEs). Methods Blood samples were collected from 89 patients with primary AMI who underwent PCI successfully before and after PCI. The levels of hs-CRPnI BNP and cTnI were measured. According to the results of the single test after operation, the patients were divided into two groups: hs-CRP high value group / hs-CRP low value group / BNP high value group / BNP low value group / cTnI high value group / cTnI low value group. According to the results of the combined test, the patients were divided into three groups: group H _ 1 with 3 items of non-high value or only with one item of high value and group H _ 2 with two items of high value) and group H _ 3 with three items of high value). The incidence of Mace was compared between groups. Results the incidence of Mace in the high value group was higher than that in the low value group, and the difference was statistically significant (P 0.01). Combined detection of hs-CRPnI BNP and cTnI levels and the incidence of Mace in H _ 1H _ 2 and H _ 3 groups were significantly different (P 0.01). The incidence of Mace in H 2 group was higher than that in H 1 group and H 3 group. Conclusion the BNP and cTnI levels of hs-CRPnI are closely related to the incidence of Mace after PCI in AMI patients.
【作者单位】：安徽医科大学第一附属医院干部心内科;滁州城市职业学院护理系;
【基金】：安徽省科技厅年度计划项目(12070403069)
【分类号】：R542.22

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