连续性血液净化治疗在重度烧伤患者救治中的应用

发布时间：2018-06-18 16:34

  本文选题：重度烧伤 + 连续性血液净化　； 参考：《肾脏病与透析肾移植杂志》2016年01期

【摘要】：目的:观察连续性血液净化(CBP)在重症烧伤患者救治中的作用。方法:7例大面积重度烧伤患者,合并全身炎症反应综合征(SIRS)/脓毒症,和(或)多脏器功能不全综合征(MODS),在接诊24h内实施CBP治疗。记录患者生命体征、血常规、血生化、肝功能、肾损伤指标,炎症指标、28d及6个月死亡率。结果:7例患者平均烧伤总面积达91.1%,28d死亡率28.6%(2/7),6个月死亡率42.9%(3/7)。患者血压、体温、炎症指标、血糖、血钠、尿量等与预后密切相关的指标相对稳定。结论:重度烧伤患者及早实施CBP治疗能减轻SIRS/脓毒症、改善内环境、保护重要脏器功能和改善预后。
[Abstract]:Objective: to observe the effect of continuous blood purification (CBP) in the treatment of severe burn patients. Methods Seven patients with large area severe burn were treated with CBP within 24 hours after treatment with systemic inflammatory response syndrome (SIRSN) / sepsis and / or multiple organ dysfunction syndrome (MODS). Vital signs, blood routine examination, blood biochemistry, liver function, renal injury index, inflammation index, 28 days and 6 months mortality were recorded. Results the average total burn area of 7 patients was 91.1 / 28d, the mortality was 28.610 / 7 / 7, and the 6-month mortality was 42.9 / 70.The average burn area of 7 cases was 91.1% / 28d. Blood pressure, body temperature, inflammation, blood glucose, sodium, urine volume and other closely related prognostic indicators are relatively stable. Conclusion: early application of CBP in severe burn patients can alleviate SIRS / sepsis, improve internal environment, protect important organ function and improve prognosis.
【作者单位】： 第二军医大学金陵医院(南京军区南京总医院)肾脏科;第二军医大学金陵医院(南京军区南京总医院)国家肾脏疾病临床医学研究中心全军肾脏病研究所;
【基金】：国家自然科学基金面上项目(81170708) 国家科技支撑计划课题(2013BAI09B04,2015BAI12B05) 江苏省临床医学科技专项(BL2012007)
【分类号】：R644
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本文编号：2036125