重症感染降阶梯治疗失败的相关性研究

发布时间：2018-06-22 05:37

  本文选题：重症感染 + 阶梯治疗　； 参考：《中国医院药学杂志》2016年04期

【摘要】：目的:对重症感染患者降阶梯治疗失败的危险因素进行研究,为合理进行降阶梯治疗提供科学依据。方法:以某院2007年1月-2014年12月412例采用降阶梯治疗重症感染患者为调查对象,由医院信息管理系统导出所需的各项调查项目,再采用Excel统一填写各项调查项目,对412例调查项目齐全的病例进行研究,数据采用SPSS 13.0统计软件进行分析,各变量现经单因素分析后,选择具有统计学差异的因素再进行非条件Logistic回归分析。结果:高龄(≥70岁)、多重耐药菌感染、低蛋白血症(30 g)、呼吸机辅助呼吸时间过长(≥7 d)为降阶梯治疗失败的危险因素,其中高龄(≥70岁)、多重耐药菌感染、低蛋白血症(30 g)为降阶梯治疗失败的独立危险因素。结论:重症感染的患者如存在高龄(≥70岁)、多重耐药菌感染、低蛋白血症(30 g)因素,则尽量不要采用降阶梯治疗。如果同时存在高龄(≥70岁)和多重耐药菌感染或高龄(≥70岁)和低蛋白血症(30 g)的重症感染患者不能采用降阶梯治疗法。
[Abstract]:Objective: to study the risk factors of the failure of descending ladder therapy in patients with severe infection. Methods: 412 patients with severe infection were investigated from January 2007 to December 2014. The items of investigation were derived from the hospital information management system, and the investigation items were filled out by Excel. 412 cases with complete investigation items were studied. The data were analyzed by SPSS 13.0 statistical software. After single factor analysis, the factors with statistical difference were selected for non-conditional logistic regression analysis. Results: old age (鈮，

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