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Padua量表及改良后Padua量表在创伤外科患者VTE风险评估中的应用效果

发布时间:2018-06-22 18:49

  本文选题:静脉血栓栓塞症 + 静脉血栓栓塞症风险评估表 ; 参考:《青岛大学》2017年硕士论文


【摘要】:目的:通过回顾性采集患者病历资料评价Padua量表及改良后Padua量表在创伤外科患者静脉血栓栓塞症风险评估中的效果。方法:回顾性收集青岛大学附属医院自2015年11月至2016年9月收入创伤外科住院的590例患者的住院资料,其中25例确诊为VTE患者。分别应用Caprini量表、Padua量表及改良后Padua量表、RAP评分对590例患者进行评分。通过分析评分结果:评价各量表评估为高危患者中确诊为静脉血栓栓塞症的患者所占比例,进行率的比较;构建受试者工作特征曲线(ROC)模型,比较改良后Padua量表与Caprini量表、Padua量表、RAP评分的灵敏度、特异度和约登指数。结果:回顾性采集590例创伤外科住院患者资料。Caprini量表评价为高危患者中阳性率占6.93%、Padua量表评价为高危患者中阳性率占8.75%、改良后Padua量表阳性率占8.42%,各量表相比差异均无统计学意义(P0.05);由构建ROC曲线模型所得:Caprini量表、Padua量表、改良后Padua量表、RAP评分评价创伤外科患者静脉血栓栓塞症风险的曲线下面积(AUC)分别为0.808(95%CI=0.754~0.862)、0.751(95%CI=0.676~0.826)、0.773(0.700~0.847)和0.774(95%CI=0.687~0.0.860),最佳切点的(Caprini量表≥3.5分、Padua量表≥3.5分、改良后Padua量表≥4.5分、RAP评分≥6.5分)的灵敏度分别为100%、96%、96%和80%,特异度分别为55.4%、55.8%、56.1%和71.5%,约登指数分别为0.554、0.518、0.521和0.515;Caprini量表、Padua量表、改良后Padua量表、RAP评分对创伤外科患者静脉血栓栓塞症的风险评估均有统计学意义(均P0.05)。结论:Padua量表及改良后Padua量表适用于对创伤外科患者静脉血栓栓塞症风险评估。
[Abstract]:Objective: to evaluate the efficacy of Padua scale and modified Padua scale in evaluating the risk of venous thromboembolism in trauma surgery patients. Methods: the data of 590 patients admitted to trauma surgery from November 2015 to September 2016 in Qingdao University affiliated Hospital were collected retrospectively. 25 of them were diagnosed as VTE patients. Caprini scale Padua scale and modified Padua scale were used to evaluate 590 patients. Through the analysis of scoring results: to evaluate the proportion and rate of patients diagnosed with venous thromboembolism (VTE) in the high risk patients assessed by various scales, to construct the model of operating characteristic curve (ROC) of subjects, and to compare the percentage of patients with venous thromboembolism (VTE). The sensitivity, specificity and Jorden index of modified Padua scale and Caprini scale / Padua scale were compared. Results: a retrospective study of 590 inpatients with trauma surgery. Caprini scale showed that the positive rate of high risk patients was 6.93% and the positive rate of Padua scale was 8.75%, and the positive rate of modified Padua scale was 8.42%. There was no statistical significance (P0.05). The area under curve (AUC) of modified Padua scale / rap score for evaluating the risk of venous thromboembolism in trauma surgery patients was 0.808 (95CI0.754 / 0.862) and 0.751 (95CI0.760.826), 0.773 (0.70070.847) and 0.774 (95CI0.6870.0.860), respectively. The sensitivity of the improved Padua scale 鈮,

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