健侧重复经颅磁刺激对脑外伤患者记忆和生活质量的影响

发布时间：2018-06-23 09:39

本文选题：脑外伤 + 重复经颅磁刺激　；参考：《中国康复理论与实践》2017年10期

【摘要】：目的观察健侧低频重复经颅磁刺激(r TMS)对脑外伤患者的记忆和生活质量的影响。方法 2013年9月至2015年6月,本院60例脑外伤后记忆功能障碍患者,随机分为对照组(n=30)和观察组(n=30)。两组均给予常规神经外科治疗。观察组在此基础上予以健侧低频r TMS治疗,每天治疗1次,每周连续治疗5 d,休息2 d,共治疗4周。观察两组患者治疗前后Rivermead行为记忆测验(RBMT)和世界卫生组织生活质量测定简表(WHOQOL-BREF)评分的差异。结果治疗后,对照组RBMT评分较治疗前无显著性差异(t=1.233,P=0.223),观察组RBMT评分较治疗前提高(t=2.186,P=0.033),两组RBMT评分无显著性差异(t=1.133,P=0.262)。治疗后,对照组WHOQOL-BREF评分仅在生理领域较治疗前显著提高(t=5.606,P0.001),观察组WHOQOL-BREF评分在生理领域、心理领域、环境领域均较治疗前明显提高(t2.879,P0.01);观察组WHOQOL-BREF评分在生理领域、心理领域和环境领域均高于对照组(t2.095,P0.05),两组社会领域评分之间无显著性差异(t=0.508,P=0.614)。结论健侧低频r TMS可能对脑外伤患者记忆功能和生活质量的改善有促进作用。
[Abstract]:Objective to observe the effect of low frequency repetitive transcranial magnetic stimulation (r TMS) on memory and quality of life in patients with traumatic brain injury. Methods from September 2013 to June 2015, 60 patients with memory impairment after traumatic brain injury in our hospital were randomly divided into control group (n = 30) and observation group (n = 30). Both groups were given routine neurosurgical treatment. The observation group was treated with normal side low frequency r TMS once a day for 5 days, rest for 2 days, and treated for 4 weeks. The difference of Rivermead Behavioral memory Test (RBMT) and World Health Organization quality of Life (WHOQOL-BREF) score before and after treatment were observed. Results after treatment, the RBMT score of the control group was not significantly different from that of the control group (t = 1.233), the RBMT score of the observation group was higher than that of the control group (t = 2.186), and there was no significant difference in the RBMT score between the two groups (t = 1.133, P = 0.262). After treatment, the WHOQOL-BREF score in the control group was significantly higher than that before treatment (t = 5.606 / P0.001). The WHOQOL-BREF score in the observation group was significantly higher in the physiological, psychological and environmental fields than that before treatment (t 2.879, P 0.01), and the WHOQOL-BREF score in the observation group was in the physiological field. The psychological and environmental fields were higher than those in the control group (t2.095P 0.05), but there was no significant difference between the two groups in the score of social field (t 0.508g / P 0.614). Conclusion low frequency r TMS may promote the improvement of memory function and quality of life in patients with brain injury.
【作者单位】：南方医科大学附属深圳宝安医院;
【基金】：广东省医学科研基金项目(No.A2008647) 深圳市科技计划项目(No.JCYJ20150402152005619)
【分类号】：R651.15

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