脓毒症患者N-末端B型利钠肽原与连续心排血量监测指标及预后的相关性
发布时间：2018-08-14 14:50
【摘要】：目的探究脓毒症患者N-末端B型利钠肽(NT-pro BNP)以及脉搏指数连续心排血量(Pi COO)监测指标与预后的相关性。方法选择脓毒症患者113例。经过1个月的治疗74例存活,39例死亡。对比存活组与死亡组患者临床资料以及不同阶段NT-pro BNP水平、治疗前的Pi CCO各指标,最后进行相关性分析。结果存活组APACHEⅡ评分显著低于死亡组,并且出现严重感染以及并发症的患者比例也显著低于死亡组;两组在第1天NT-pro BNP水平比较无差异,存活组在第3、5、7天NT-pro BNP水平均显著低于死亡组;两组胸腔内血容量指数(ITBVI)、体外循环阻力指数(SVRI)无显著差异,但存活组心脏指数(CI)高于死亡组,而血管外肺水指数(EVLWI)、肺毛细血管通透性指数(PVPI)低于死亡组(均P0.05)。通过相关性分析得到:NT-pro BNP、EVLWI、PVPI与死亡率存在明显正相关(r=0.741,P=0.000;r=0.731,P=0.000;r=0.814,P=0.000),CI与死亡率存在明显负相关(r=-0.261,P=0.000)。结论脓毒症患者血浆中NT-pro BNP水平随着病情加重而逐渐升高,结合APACHEⅡ评分两者越高预后越差。Pi COO监测指标也与预后存在显著相关性,对临床治疗及预后评估具有非常高的指导价值。
[Abstract]:Objective to investigate the relationship between the prognostic value of N-terminal B-type natriuretic peptide (NT-pro BNP) and continuous cardiac output (Pi COO) of pulse index in patients with sepsis. Methods 113 patients with sepsis were selected. After 1 month treatment, 74 patients survived and 39 died. The clinical data and NT-pro BNP levels in different stages of survival group and death group were compared, and the indexes of Pi CCO before treatment were analyzed. Results the score of APACHE 鈪，
本文编号：2183206
[Abstract]:Objective to investigate the relationship between the prognostic value of N-terminal B-type natriuretic peptide (NT-pro BNP) and continuous cardiac output (Pi COO) of pulse index in patients with sepsis. Methods 113 patients with sepsis were selected. After 1 month treatment, 74 patients survived and 39 died. The clinical data and NT-pro BNP levels in different stages of survival group and death group were compared, and the indexes of Pi CCO before treatment were analyzed. Results the score of APACHE 鈪，
本文编号：2183206
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