芪参益气滴丸对老年急性心肌梗死患者超敏C反应蛋白和心脏功能的影响

发布时间：2018-10-09 16:54

【摘要】：目的观察中药芪参益气滴丸对老年急性心肌梗死患者C反应蛋白及心脏功能的影响。方法老年心肌梗死患者126例依据正规内科治疗的基础上是否行介入手术分为内科治疗组、内科观察组、介入治疗组、介入观察组,治疗组加用芪参益气滴丸,检查治疗前及治疗1周后C反应蛋白(CRP)、脑钠肽(BNP),超声心动图测量治疗前及治疗8周后左室舒张末期内径(LVEDd)、左室舒张末期容积(LVEDV)、左室收缩末期容积(LVESV)、左室射血分数(LVEF)。结果介入组内与内科组内2组比较,治疗组BNP、CRP均较观察组显著下降(P0.05),介入治疗组、内科治疗组的LVESV、LVEDV均较对应的观察组低,差异有统计学意义(P0.05),而LVEDd差异无统计学意义(P0.05),介入治疗组,内科治疗LVEF均高于对应的观察组,差异有统计学意义(P0.05);同时,介入治疗组与内科治疗组相比,前者LVEDd、LVEDV均低于后者(P0.01),前者LVEF高于后者(P0.01),差异有统计学意义。结论常规治疗基础上联用芪参益气滴丸可以显著地提高左室功能,抑制心肌重构,减少心肌梗死后心衰的发生,而且,这些作用在血运重建后仍有良好的表现。
[Abstract]:Objective to observe the effect of Qishen Yiqi dropping pill on C reactive protein and cardiac function in elderly patients with acute myocardial infarction. Methods 126 elderly patients with myocardial infarction were divided into three groups: medical treatment group, medical observation group, interventional treatment group, interventional observation group, treatment group and Qishen Yiqi dropping pills. C-reactive protein (CRP), brain natriuretic peptide (BNP), echocardiography before and 1 week after treatment left ventricular end-diastolic diameter (LVEDd), left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), left ventricular ejection fraction (LVEF). Results in the interventional group and the internal medicine group, the BNP,CRP of the treatment group was significantly lower than that of the observation group (P0.05). The LVESV,LVEDV of the interventional treatment group and the medical treatment group were lower than that of the corresponding observation group. The difference was statistically significant (P0.05), but the difference of LVEDd was not statistically significant (P0.05). The LVEF of interventional treatment group and internal medicine treatment group were higher than those of corresponding observation group (P0.05). At the same time, the interventional treatment group was compared with the medical treatment group. The LVEDd,LVEDV of the former was lower than that of the latter (P0.01), and the LVEF of the former was higher than that of the latter (P0.01). Conclusion Qishen Yiqi dropping pill combined with conventional therapy can significantly improve left ventricular function, inhibit myocardial remodeling and reduce heart failure after myocardial infarction, and these effects still have good performance after revascularization.
【作者单位】：河南省南阳市第一人民医院内三科;
【分类号】：R542.22

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