脓毒血症患者体内乳酸清除及正常化对延缓器官衰竭的作用

发布时间：2018-11-14 13:22

【摘要】：目的评估脓毒血症患者体内乳酸清除及正常化对延缓持续性器官衰竭的作用。方法选择住院治疗的脓毒血症患者110例(并发感染和伴有器官功能衰竭)。接受治疗4 h后测量乳酸含量(若乳酸含量降低≥10%,则为乳酸清除;若乳酸浓度2 mmol/L,则为正常化水平);同时,接受治疗48 h后,用实验室和临床相结合的手段检测持续性器官功能衰竭程度。结果接受治疗4 h后,88例(80%)患者乳酸含量处于正常化水平;99例(90%)患者乳酸清除。48 h后器官衰竭的评价结果表明,乳酸含量正常化水平与降低持续性器官功能衰竭发生率有关(P0.05);乳酸清除与降低持续性器官功能衰竭发生率无关(P0.05)。结论在脓毒血症伴有器官功能衰竭的患者中,4 h以内乳酸含量的正常化水平与降低持续性器官衰竭发生率有关,抢救脓毒血症患者应提倡进行连续乳酸含量测定。
[Abstract]:Objective to evaluate the effect of lactate clearance and normalization on persistent organ failure in patients with sepsis. Methods 110 patients with sepsis (complicated with infection and organ failure) were selected. The content of lactic acid was measured 4 hours after treatment (if the content of lactic acid was decreased 鈮，

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