集束化治疗依从率对脓毒血症休克患者的疗效及预后影响的研究

发布时间：2018-11-18 16:33

【摘要】：目的研究集束化治疗依从率对脓毒血症休克患者的疗效及预后情况,为临床治疗提供参考依据。方法分析2013年1月-2014年6月于医院接受治疗的78例脓毒血症休克患者的临床资料,将42例接受集束化治疗的患者列为观察组,把36例采用常规治疗的脓毒血症休克患者纳为对照组;观察两组患者依从性和相关预后指标。结果 78例脓毒血症休克患者感染病原菌主要以革兰阴性菌感染为主,占70.51%;观察组患者6h、24h时的平均动脉压(MAP)、中心静脉压(CVP)、中心静脉血氧饱和度(ScvO_2)、动脉血乳酸水平高于对照组,差异有统计学意义(P0.05);治疗后,观察组患者的住院时间、急性生理与慢性健康(APACHE Ⅱ)评分、序贯器官衰竭估计(SOFA)评分显著低于对照组,差异有统计学意义(P0.05);集束化治疗依从组患者的28d生存率显著高于常规治疗依从组患者,差异有统计学意义(P0.05)。结论提高医务人员对于脓毒血症休克治疗的依从性可以有效改善患者血液循环功能,降低患者的病死率,对于脓毒血症休克早期的治疗具有良好的临床实用价值。
[Abstract]:Objective to study the effect and prognosis of cluster therapy compliance rate in patients with sepsis shock and to provide reference for clinical treatment. Methods the clinical data of 78 patients with sepsis shock treated in hospital from January 2013 to June 2014 were analyzed. 42 patients who received cluster therapy were included as observation group. 36 patients with sepsis shock who were treated with routine therapy were included as control group. Compliance and prognostic indexes were observed in both groups. Results the main pathogens of 78 septic shock patients were Gram-negative bacteria (70.51%). The mean arterial pressure (MAP),) central venous pressure (CVP),) central venous oxygen saturation (ScvO_2) and arterial lactate level were significantly higher in the observation group than in the control group at 6 h or 24 h (P0.05). After treatment, the hospitalization time, acute physiological and chronic health (APACHE 鈪，

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