磷酸肌酸钠对脓毒症患者心功能保护作用研究

发布时间：2018-11-28 20:40

【摘要】：探讨磷酸肌酸钠对脓毒症患者心功能保护作用。选取脓毒症患者70例随机分为常规治疗组(脓毒症常规治疗)和CP组(脓毒症常规治疗基础上加用CP),观察患者入ICU 0d、3d、7d外周血BNP水平、APACHEⅡ评分及入ICU 0d、7d LVEF、LVED、CO变化。发现入ICU 3d、7d与对照组比较BNP明显下降;CP组入ICU 7d时LVEF、CO较入ICU 0d有改善,LVED虽得到改善,但无统计学意义,治疗7d后CP组LVEF、CO较常规治疗组明显改善,APACHEⅡ评分降低、病死率降低。提示在脓毒症常规治疗基础上加用磷酸肌酸钠可改善脓毒症患者心功能,降低死亡率,改善预后。
[Abstract]:To investigate the protective effect of creatine phosphate sodium on cardiac function in septic patients. 70 patients with sepsis were randomly divided into conventional treatment group (conventional sepsis treatment) and CP group (on the basis of conventional treatment of sepsis). The peripheral blood BNP level, APACHE 鈪，

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