自动功能成像评价急性心肌梗死左室纵向应变的研究
发布时间：2019-02-18 17:58
【摘要】：研究目的：应用自动功能成像技术（AFI）定量分析AMI患者左室纵向应变，分析其与冠状动脉造影的相关性，探讨AFI对诊断急性心肌梗死的应用价值。 研究方法：在入院48小时内分别对AMI患者和对照受检者各30例行超声心动图检查，记录连续3个心动周期的左室心尖长轴、心尖四腔和心尖两腔二维灰阶动态图像以及左室心尖五腔观的主动脉血流频谱静态图像。应用AFI技术实时获取左室纵向峰值应变（LPSS）牛眼图及左室整体应变平均值，并进行重复性检测。记录AMI患者入院后的冠状动脉造影结果，比较AFI与冠状动脉造影的一致性。 结果:与对照组相比，心肌梗死组左室各节段LPSS和左室整体应变平均值均明显减低(P0.001)，牛眼图的颜色不完全一致。左室整体应变平均值与冠状动脉狭窄率呈正相关（r=0.56，P0.05）。 AFI测量的左室LPSS有较高的可重复性。 结论：AFI可以发现心肌梗死的发生，并对其室壁运动进行量化分析。左室整体应变平均值可以反映心肌梗死的严重程度。AFI的技术稳定，可靠性高；操作人为误差小，测量值可信度高。AFI作为一种简便易行的二维斑点追踪技术，可以诊断和评价AMI，有广泛的临床应用价值。
[Abstract]:Objective: to analyze the relationship between left ventricular longitudinal strain and coronary angiography (CAG) by automatic functional imaging (AFI) in patients with AMI, and to explore the value of AFI in the diagnosis of acute myocardial infarction (AMI). Methods: echocardiography was performed in 30 AMI patients and 30 control subjects within 48 hours of admission. The left ventricular apical long axis was recorded in 3 consecutive cardiac cycles. Two dimensional gray-scale dynamic images of apical and apical four lumens and five lumen view of left ventricular apex were obtained. The longitudinal peak strain of left ventricle (LPSS) and the mean value of global strain of left ventricle were obtained by AFI technique in real time. The results of coronary angiography of AMI patients after admission were recorded and the consistency between AFI and coronary angiography was compared. Results: compared with the control group, the mean values of LPSS and global strain of left ventricle in myocardial infarction group were significantly lower than those in control group (P0. 001), and the color of bovine ophthalmogram was not completely consistent. The mean global strain of left ventricle was positively correlated with the rate of coronary artery stenosis (r = 0.56, P 0.05). Left ventricular LPSS measured by AFI has high reproducibility. Conclusion: AFI can detect myocardial infarction and analyze its wall motion quantitatively. The mean global strain of left ventricle can reflect the severity of myocardial infarction. The technique of AFI is stable and reliable. As a simple two-dimensional speckle tracing technique, AFI can be used to diagnose and evaluate AMI,.
【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R445.2;R542.22
[Abstract]:Objective: to analyze the relationship between left ventricular longitudinal strain and coronary angiography (CAG) by automatic functional imaging (AFI) in patients with AMI, and to explore the value of AFI in the diagnosis of acute myocardial infarction (AMI). Methods: echocardiography was performed in 30 AMI patients and 30 control subjects within 48 hours of admission. The left ventricular apical long axis was recorded in 3 consecutive cardiac cycles. Two dimensional gray-scale dynamic images of apical and apical four lumens and five lumen view of left ventricular apex were obtained. The longitudinal peak strain of left ventricle (LPSS) and the mean value of global strain of left ventricle were obtained by AFI technique in real time. The results of coronary angiography of AMI patients after admission were recorded and the consistency between AFI and coronary angiography was compared. Results: compared with the control group, the mean values of LPSS and global strain of left ventricle in myocardial infarction group were significantly lower than those in control group (P0. 001), and the color of bovine ophthalmogram was not completely consistent. The mean global strain of left ventricle was positively correlated with the rate of coronary artery stenosis (r = 0.56, P 0.05). Left ventricular LPSS measured by AFI has high reproducibility. Conclusion: AFI can detect myocardial infarction and analyze its wall motion quantitatively. The mean global strain of left ventricle can reflect the severity of myocardial infarction. The technique of AFI is stable and reliable. As a simple two-dimensional speckle tracing technique, AFI can be used to diagnose and evaluate AMI,.
【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R445.2;R542.22
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