老年房颤合并急性心肌梗死患者瑞替普酶溶栓后窦房结功能与心脏型脂肪酸结合蛋白的相关性

发布时间：2019-03-02 15:16

【摘要】：目的研究老年房颤合并急性心肌梗死(AMI)患者瑞替普酶溶栓后窦房结功能的恢复与心肌代谢物心脏型脂肪酸结合蛋白(HFABP)之间的相关性及对预后评估的价值。方法选择发病时间3 h的老年房颤合并AMI患者给予瑞替普酶溶栓治疗,溶栓再通86例,转为窦性心律者33例,未转复者53例,记录房颤转为窦性心律瞬间心室率,未转复的房颤心室率变化,同时检测H-FABP及甲状腺激素水平,观察其对预后评估的临床意义。结果溶栓后转为窦性心律组33例,心室率越快H-FABP数值越低而甲状腺激素水平越高;未转复组房颤心室率前后变化与HFABP关系变化不明显但与甲状腺激素水平呈正相关。结论瑞替普酶溶栓效果肯定,H-FABP是诊断和判断AMI患者预后的更灵敏的指标,可更早期诊断窦房结损伤程度,判断预后。
[Abstract]:Objective to study the relationship between the recovery of sinus node function and cardiac fatty acid binding protein (HFABP) in elderly patients with atrial fibrillation complicated with acute myocardial infarction (AMI) after thrombolytic therapy with Ritteppase and its prognostic value. Methods the elderly patients with atrial fibrillation complicated with AMI at 3 hours after onset were treated with Ritteppase thrombolytic therapy. There were 86 cases of thrombolysis, 33 cases of sinus rhythm and 53 cases of unrecovered atrial fibrillation. The transient ventricular rate of atrial fibrillation converted to sinus rhythm was recorded. The changes of ventricular rate of atrial fibrillation and the levels of H-FABP and thyroid hormone were measured to evaluate the clinical significance of the changes in prognosis. Results in the group of 33 patients with sinus rhythm after thrombolysis, the faster the ventricular rate was, the lower the value of H-FABP and the higher the level of thyroid hormone, but there was a positive correlation between the change of ventricular rate before and after atrial fibrillation and the level of thyroid hormone, but there was no significant correlation between the change of ventricular rate and the level of thyroid hormone in the group without thrombolysis. Conclusion H-FABP is a more sensitive index to diagnose and judge the prognosis of patients with AMI, and it can diagnose the degree of sinoatrial node injury more early and judge the prognosis.
【作者单位】：邢台医学高等专科学校第二附属医院心内科;
【分类号】：R541.75;R542.22

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