老年非瓣膜性房颤伴急性脑梗死患者的血浆尿酸、脑钠肽水平变化及与CHADS2评分的关系

发布时间：2019-04-19 21:03

【摘要】：目的了解老年非瓣膜性房颤伴急性脑梗死患者的血浆尿酸、脑钠肽(BNP)水平的变化意义及与CHADS2的关系。方法对入住该院的188例老年非瓣膜性房颤患者分为急性脑梗死及非急性脑梗死组,测定BNP、尿酸水平,并了解其在CHADS2评分中的变化。结果急性脑梗死组的BNP及尿酸水平较非急性脑梗死组明显增高(均P=0.000)。随着CHADS2评分的增高,BNP水平逐渐升高(P=0.036),但尿酸无类似趋势。结论 BNP、尿酸增高可能是老年非瓣膜病心房颤动患者发生脑梗死的危险因素,且随着CHADS2分值升高,BNP水平也越高。
[Abstract]:Aim to investigate the changes of plasma uric acid and brain natriuretic peptide (BNP) levels in elderly patients with nonvalvular atrial fibrillation with acute cerebral infarction (ACI) and its relationship with CHADS2. Methods 188 elderly patients with non-valvular atrial fibrillation were divided into two groups: acute cerebral infarction group and non-acute cerebral infarction group. The level of BNP, uric acid was measured and the changes in CHADS2 score were observed. Results the levels of BNP and uric acid in the acute cerebral infarction group were significantly higher than those in the non-acute cerebral infarction group (P < 0. 000). With the increase of CHADS2 score, the level of BNP increased gradually (P < 0. 036), but there was no similar tendency of uric acid. Conclusion the increase of BNP, uric acid may be a risk factor for cerebral infarction in elderly patients with non-valvular atrial fibrillation, and the higher the level of BNP is with the increase of CHADS2 score.
【作者单位】： 海南省人民医院医疗保健三区;
【基金】：海南省卫计委资金资助项目(No.13A200003)
【分类号】：R541.75;R743.3

【相似文献】

相关期刊论文 前3条

1 毕文静;李颖;任卫东;杨军;孙菲菲;;应用CHADS2评分预测非瓣膜性心房颤动患者左心房/左心耳血栓[J];中国医学影像技术;2013年03期

2 林雪;陈亚平;;比较CHADS2、CHA2DS2-VASC两种评分法在房颤患者发生脑卒中的风险评估[J];中国实用神经疾病杂志;2014年10期

3 ;[J];;年期

相关硕士学位论文 前2条

1 魏博;比较CHADS2、CHA2DS2-VASc、R2-CHADS2三种评分对非瓣膜性房颤患者卒中风险分层作用[D];重庆医科大学;2015年

2 刘燕;非瓣膜性心房颤动CHADS2评分低中危串者脑卒中危险因素的研究[D];复旦大学;2013年

，

本文编号：2461280