血清尿酸、白细胞介素-6、高敏C反应蛋白水平在老年急性缺血性脑卒中患者预后评估中的价值
发布时间：2019-04-22 10:29
【摘要】：目的探讨血清尿酸(UA)、白细胞介素(IL)-6、高敏C反应蛋白(hs-CRP)水平对老年急性缺血性脑卒中(AIS)患者预后的评估价值。方法选取该院2013年1月至2015年1月老年AIS患者148例作为病例组,参照Adamas分类法将患者分为实验组(大面积AIS)与对照组(非大面积AIS),同期选取健康体检者75例作为正常组,均检测血清UA、IL-6、hs-CRP水平,分析三者对预后的评估价值。结果实验、对照组患者血清UA、IL-6、hs-CRP水平明显高于正常组(P0.05),且实验组明显高于对照组(P0.05)。实验、对照组患者美国国立卫生研究院脑卒中量表(NIHSS)评分、急性生理和慢性健康状况评价系统(APPACHE)Ⅱ评分高于正常组患者(P0.05),格拉斯哥昏迷评分量表(GCS)评分明显低于正常组(P0.05);实验组NIHSS评分、APPACHEⅡ评分明显高于对照组(P0.05),GCS评分明显低于对照组(P0.05)。经Pearson相关性分析,UA、IL-6、hsCRP与NIHSS评分、APPACHEⅡ评分呈正相关(P0.05),UA、IL-6、hs-CRP与GCS评分呈负相关(P0.05)。结论老年AIS患者UA、IL-6、hs-CRP水平显著增高,其增高幅度与预后状况具有明显的相关性。
[Abstract]:Objective to evaluate the prognostic value of serum uric acid (UA), interleukin-6 (IL)-6) and Gao Min C-reactive protein (hs-CRP) levels in elderly patients with acute ischemic stroke (AIS). Methods from January 2013 to January 2015, 148 elderly patients with AIS were selected as the case group. According to the Adamas classification, the patients were divided into two groups: experimental group (large area AIS) and control group (non-large area AIS), 75 healthy subjects were selected as normal group). Serum UA,IL-6,hs-CRP levels were measured and their prognostic value was analyzed. Results the level of serum UA,IL-6,hs-CRP in the control group was significantly higher than that in the normal group (P0.05), and the level in the experimental group was significantly higher than that in the control group (P0.05). In the experiment, the (NIHSS) score of the NIH Stroke scale and the (APPACHE) 鈪，
本文编号：2462759
[Abstract]:Objective to evaluate the prognostic value of serum uric acid (UA), interleukin-6 (IL)-6) and Gao Min C-reactive protein (hs-CRP) levels in elderly patients with acute ischemic stroke (AIS). Methods from January 2013 to January 2015, 148 elderly patients with AIS were selected as the case group. According to the Adamas classification, the patients were divided into two groups: experimental group (large area AIS) and control group (non-large area AIS), 75 healthy subjects were selected as normal group). Serum UA,IL-6,hs-CRP levels were measured and their prognostic value was analyzed. Results the level of serum UA,IL-6,hs-CRP in the control group was significantly higher than that in the normal group (P0.05), and the level in the experimental group was significantly higher than that in the control group (P0.05). In the experiment, the (NIHSS) score of the NIH Stroke scale and the (APPACHE) 鈪，
本文编号：2462759
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