脑白质病变与急性脑梗死患者近期预后的关系

发布时间：2019-06-18 12:50

【摘要】：目的探讨脑白质病变(WML)与急性脑梗死(ACI)患者近期预后的关系。方法选择合并WML的ACI患者40例(WML组),同期未合并WML的ACI患者40例(对照组)。收集所有患者病历资料(一般资料、入院时实验室检查结果),采用改良Rankin预后等级量表评分(MRS)评价患者近期(出院1个月)预后;根据MRS将患者分为预后良好组46例、预后不良组34例;用受试者工作特征(ROC)曲线评价WML对ACI预后评价的价值;采用二元Logistic回归分析WML与ACI患者近期预后的关系。结果与对照组比较,WML组年龄、MRS评分高(P均0.05);与预后良好组比较,预后不良组年龄、WML患病率、入院时美国国立卫生院神经功能缺损量表(NIHSS)评分高(P均0.05);年龄、WML、NIHSS评分评估ACI患者近期预后的ROC曲线下面积分别为0.71、0.64、0.74;经二元Logistic回归分析发现,WML是ACI患者近期预后的危险因素(OR=2.65,P0.05)。结论合并WML的ACI患者近期预后不良。
[Abstract]:Objective to investigate the relationship between (WML) and short-term prognosis of patients with acute cerebral infarction (ACI). Methods 40 patients with ACI complicated with WML (WML group) and 40 patients with ACI without WML at the same time (control group) were selected. The clinical data of all patients (general data, laboratory results at admission) were collected, and the short-term prognosis of patients was evaluated by modified Rankin prognosis rating scale (MRS). According to MRS, the patients were divided into good prognosis group (46 cases) and poor prognosis group (34 cases). The value of WML in evaluating the prognosis of ACI was evaluated by (ROC) curve of subjects' working characteristics. The relationship between WML and short-term prognosis of ACI patients was analyzed by binary Logistic regression. Results compared with the control group, the age and MRS score of the WML group were higher than those of the control group, and the age of the poor prognosis group, the prevalence of WML and the (NIHSS) score of the neurologic deficit scale of the National Hospital of Health at admission were higher than those of the control group, and the area under the ROC curve of age and WML,NIHSS score for evaluating the short-term prognosis of ACI patients were 0.71, 0.64 and 0.74, respectively. Binary Logistic regression analysis showed that WML was a risk factor for short-term prognosis of ACI patients (OR=2.65,P0.05). Conclusion the short-term prognosis of ACI patients with WML is poor.
【作者单位】：安徽省医科大学第一附属医院;寿县县医院;
【基金】：安徽省自然科学基金资助项目(1508085SMH228)
【分类号】：R743.33

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