甲基苯丙胺依赖患者脱毒治疗期间医院感染相关因素分析

发布时间：2018-01-01 18:21

本文关键词：甲基苯丙胺依赖患者脱毒治疗期间医院感染相关因素分析　出处：《中国药房》2016年11期 　论文类型：期刊论文

【摘要】：目的:为甲基苯丙胺依赖患者脱毒治疗期间继发医院感染的预防及治疗提供参考。方法:回顾性分析我院2011年11月-2015年10月318例甲基苯丙胺依赖患者脱毒治疗期间的临床资料,分析感染率、感染部位、感染危险因素、病原菌分布特征等相关因素。结果:318例甲基苯丙胺依赖患者脱毒治疗期间继发医院感染122例,感染率为38.4%。患者医院感染部位主要分布在呼吸系统和消化系统;病原菌主要以肺炎克雷伯菌、肺炎链球菌、金黄色葡萄球菌为主;合并基础疾病、血清白蛋白水平低、有侵入性操作、抗菌药物使用、白细胞计数低的患者发生医院感染率较高,分别为53.5%、58.9%、47.8%、47.4%、45.9%,是医院感染的危险因素,差异有统计学意义(P0.05)。结论:甲基苯丙胺依赖患者脱毒治疗期间继发医院感染率高,医务人员应积极处置基础疾病,严格且尽可能减少各项侵习性操作,采取多种措施综合干预来减少医院感染。
[Abstract]:Objective: to provide a reference for the prevention and treatment of secondary nosocomial infection in methamphetamine dependent patients during detoxification treatment. The clinical data of 318 patients with methamphetamine dependence during detoxification from November 2011 to October 2015 in our hospital were analyzed retrospectively. Results 122 cases of nosocomial infection occurred during detoxification treatment in 318 patients with methamphetamine dependence. The infection rate was 38.4%. The nosocomial infection was mainly located in the respiratory system and digestive system. The main pathogens were Klebsiella pneumoniae, Streptococcus pneumoniae and Staphylococcus aureus. The nosocomial infection rate was higher in patients with basic diseases, low serum albumin level, invasive operation, use of antimicrobial agents and low white blood cell count, which were 53.58.9% and 47.8%, respectively. It is a risk factor of nosocomial infection, and the difference is statistically significant (P0.055.Conclusion: the secondary nosocomial infection rate of methamphetamine dependent patients is high during detoxification treatment. Medical personnel should actively deal with basic diseases, strictly and as far as possible reduce the invasive operation, take a variety of comprehensive measures to reduce nosocomial infection.
【作者单位】：宜宾市第四人民医院;
【分类号】：R749.6
【正文快照】： 甲基苯丙胺(Methamphetamine,MA)又称脱氧麻黄碱或甲基安非他明,目前已成国际公害,不但损害患者个人身心健康,导致经济损失巨大,而且严重扰乱社会和谐。临床观察表明,MA依赖患者免疫系统功能低下,易发生各种感染[1],由于不洁净注射器的交叉使用,使其血源性传播的感染率远高于

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