注意力缺陷多动障碍相关因素及抑肝散治疗效果的临床研究

发布时间：2018-01-18 08:18

  本文关键词：注意力缺陷多动障碍相关因素及抑肝散治疗效果的临床研究　出处：《中国临床药理学杂志》2015年15期 　论文类型：期刊论文

  更多相关文章： 抑肝散 小儿多动症 家庭环境 生活习惯 环境毒物

【摘要】：目的探讨注意力缺陷多动障碍(ADHD)的临床相关因素,评价抑肝散治疗小儿多动症的临床效果。方法入选120例ADHD患儿作为研究对象,健康儿童120例作为对照组,通过问卷调查形式评价家庭环境、儿童生活习惯、儿童环境毒物接触情况对ADHD的影响。另选取患儿中证属脾虚肝亢者75例,其中试验组38例,对照组37例,对照组给予单纯行为治疗,每周3次;试验组在对照组治疗基础上,口服加味抑肝散150 m L,一日2次,疗程为8周,分别于入组前,治疗后4,8周行中医证候积分评定和疗效判断。结果父母学历低于初中、采取责罚教育方式、家庭月收入低于每月3000元、单亲或隔代抚养家庭、人工喂养、父母为独生子女均为发生ADHD的危险因素。作息不规律、缺乏爱好、睡眠紊乱、易食零食,接触增塑剂(DEHP)次数越多及玩手机次数越频繁更易患ADHD。试验组控显率为52.63%,总有效率为86.84%;对照组控显率为24.32%,总有效率为43.24%,试验组疗效优于对照组(P0.01)。治疗8周后,2组中医证候积分均显著降低(P0.01),试验组治疗后中医证候积分低于对照组,其改善程度更显著。结论 ADHD发生与家庭环境、儿童生活习惯及接触环境毒物有一定关系;抑肝散治疗脾虚肝亢型ADHD疗效确切。
[Abstract]:Objective to investigate the clinical related factors of attention deficit hyperactivity disorder (ADHD) and evaluate the clinical effect of Yigan San in treating ADHD in children with ADHD. Methods 120 children with ADHD were selected as the study objects. 120 healthy children were used as control group to evaluate family environment and children's living habits by questionnaire. In addition, 75 children with spleen deficiency and liver hyperactivity were selected, including 38 cases in the experimental group, 37 cases in the control group, and 3 times a week in the control group. Experimental group in the control group on the basis of treatment, oral Jiawei Yi Gan San 150ml, on 1st, twice, the course of treatment is 8 weeks, respectively before entering the group, 4 after treatment. Results the parents' educational background was lower than junior high school, the family monthly income was less than 3000 yuan per month, single parent or other generations raised family, artificial feeding. Parents are the only child of the risk factors for the occurrence of ADHD. Irregular work and rest, lack of hobbies, sleep disorder, easy to eat snacks. The more times of contact with plasticizer DEHPand the more frequency of playing mobile phones, the more susceptible to ADHD.The control rate of the test group was 52.63 and the total effective rate was 86.84. The control rate of the control group was 24.322.The total effective rate was 43.24.The curative effect of the experimental group was better than that of the control group (P 0.01). After 8 weeks of treatment, the effect of the test group was better than that of the control group. The scores of TCM syndromes in the two groups were significantly lower than those in the control group, and the scores of TCM syndromes in the experimental group were lower than those in the control group. Conclusion the occurrence of ADHD and the family environment are more significant. Children's living habits and exposure to environmental poisons are related to a certain extent; The curative effect of Yigan Powder on ADHD with spleen deficiency and liver hyperactivity was definite.
【作者单位】： 唐山市工人医院中医科;
【基金】：唐山市级发展与指导计划基金资助项目(10130233a)
【分类号】：R749.94
【正文快照】： 常亚军,刘秀敏,闫仲凯(唐山市工人医院中医科,河北唐山063021)CHANG Ya-jun,LIU Xiu-min,YAN Zhong-kai(Department Traditional Chinese Medi-cine,Tangshan Worker's HospitalAffiliated Rehabilitation Hospital,Tangshan 063021,Hebei Province,China)注意力缺陷多动障碍(

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