乌鲁木齐维吾尔族男性美沙酮维持治疗者、吸毒者和一般人群性功能的调查研究

发布时间：2018-02-09 20:15

本文关键词： 美沙酮维持治疗静脉吸毒性功能勃起功能障碍维吾尔族男性　出处：《新疆医科大学》2012年硕士论文　论文类型：学位论文

【摘要】：目的：了解乌鲁木齐市海洛因成瘾人群在接受美沙酮维持治疗(Methadonemaintenance treatment，MMT)后的性功能状况，探讨美沙酮对吸毒人群性功能的潜在影响，，分析原因及提供对策。方法：采用“自制调查表”、“勃起功能障碍对生活质量影响的调查表”和“国际勃起功能指数问卷调查表（IIEF-5）”，对乌鲁木齐市7个MMT门诊参加治疗6个月以上的131名维吾尔族男性、乌鲁木齐市强制戒毒所强制收留时间不超过一个月的进行戒毒的129名维吾尔族男性以及乌鲁木齐市四个社区管辖内130名从未吸毒的维吾尔族男性居民进行面对面访谈并填写问卷。通过单因素分析和二分类Logistic回归分析来探讨各组男性性功能障碍的影响因素。结果:通过单因素分析结果显示，三组人群在性欲、勃起维持时间、早泄、近三个月的性行为次数、性生活的满意程度，勃起功能指数及勃起功能障碍对生活质量的影响程度等方面差异均有统计学意义（P＜0.001）。多因素logistic回归分析可知，分组不同的人群性功能状况有一定的差异。与一般人群相比，MMT组和吸毒组人群的性功能状况差异均有统计学意义（OR=17.340,5.590~53.782）,(OR=6.964，2.883~16.825)。而MMT组和吸毒组人群的性功能状况相互比较，差异无统计学意义（OR=0.402, P=0.075）。影响性功能状况的因素有：年龄和前列腺炎。与20～29岁组男性相比，30～39岁组和≥40岁组男性性功能状况差异均有统计学意义（OR=2.506,1.218~5.158），（OR=2.763,1.016~7.519）。患有前列腺炎的男性发生性功能障碍的危险性是未患前列腺炎者的2.257倍（OR=2.257,1.021~4.993）。结论：吸毒会导致男性性功能障碍。美沙酮维持治疗不是导致男性海洛因成瘾者性功能障碍的主要原因，但大剂量的药物维持治疗会加重对性功能的影响。低维持剂量则会改善性功能状况。因此调整好维持剂量将能有效地改善该人群的性功能状况。
[Abstract]:Objective: to investigate the sexual function of heroin addicts in Urumqi after receiving methadone maintenance therapy (MMTT), and to explore the potential effect of methadone on sexual function of drug addicts. Methods: Self-made questionnaire, questionnaire on the influence of erectile dysfunction on quality of life and International erectile Index questionnaire (IIEF-5) were used to treat 7 MMT outpatients in Urumqi. 131 Uighur men treated for more than six months, In Urumqi, 129 Uygur men who had been detoxified for no more than a month and 130 Uighur male residents who had never used drugs in four communities under the jurisdiction of Urumqi City were held face to face in a forced drug treatment center for no more than one month. To investigate the influencing factors of male sexual dysfunction in each group by univariate analysis and two-classification Logistic regression analysis. Results: univariate analysis showed that, Three groups of people in the sexual desire, erectile maintenance time, premature ejaculation, the last three months of sexual activity, sexual satisfaction, There were significant differences in erectile function index and the degree of influence of erectile dysfunction on quality of life (P < 0.001). Multivariate logistic regression analysis showed that there were significant differences in the index of erectile function and the degree of influence of erectile dysfunction on quality of life. There were some differences in sexual function status among different groups of people. There were significant differences in sexual function status between MMT group and drug addicts group compared with the general population. There were significant differences in sexual function status between MMT group and drug addicts group, and the sexual function status of MMT group and drug addicts group were compared with each other. There was no significant difference in sexual function status between male and female. The factors influencing sexual function were age and prostatitis. There were significant differences in sexual function between 30 and 39 years old men and more than 40 years old men compared with 20 and 29 years old men. There was significant difference in the sexual function status of OR2.5061.21885.1580.There were significant differences in the sexual function status of the men with prostatitis (OR 2.763P 1.0167.519). The risk of sexual dysfunction in men was 2.257 times as high as that in patients without prostatitis. Conclusion: drug use may lead to sexual dysfunction in men. Methadone maintenance therapy is not the main cause of sexual dysfunction in heroin addicts. However, large dose of drug maintenance therapy will aggravate the influence on sexual function. Low maintenance dose will improve sexual function. Therefore, adjusting maintenance dose can effectively improve the sexual function of the population.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R749.64

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