强迫症决策功能的神经机制和评估

发布时间：2018-03-14 00:49

本文选题：强迫症　切入点：决策功能　出处：《上海交通大学学报(医学版)》2017年07期 　论文类型：期刊论文

【摘要】：强迫症是一种复杂的慢性致残性神经精神障碍,从神经生物学基础而言,其与大脑的一些重要脑区如眶额皮质、前扣带皮层有关。同时,神经影像学研究也表明与决策功能相关的脑区有眶额皮质、背外侧前额叶等。由此可见,强迫症与决策功能有一定的神经生物学相关性。决策功能受损是强迫症的典型临床表现,而且强迫症的发病与异常决策功能也有相关性。通常决策可分为风险模糊下决策和风险明确下决策,常用的评估前者的任务主要是爱荷华博弈任务,评估后者的有色子任务等。该文对强迫症中决策功能的神经机制和评估进行综述。
[Abstract]:Obsessive-compulsive disorder (OCD) is a complex chronic disabling neuropsychiatric disorder associated with important brain regions such as the orbital frontal cortex and the anterior cingulate cortex. Neuroimaging studies also show that the regions of the brain associated with decision-making function include the orbital frontal cortex, the dorsolateral prefrontal lobe, and so on. Obsessive-compulsive disorder (OCD) has a certain neurobiological correlation with decision-making function, which is a typical clinical manifestation of obsessive-compulsive disorder (OCD). The incidence of obsessive-compulsive disorder (OCD) is also correlated with abnormal decision making function. Usually, the decision can be divided into fuzzy decision and explicit decision. The main task of evaluating the former is the Iowa game. The neuromechanism and evaluation of decision-making function in obsessive-compulsive disorder (OCD) were reviewed.
【作者单位】：上海交通大学医学院;上海交通大学医学院附属瑞金医院心理科;上海交通大学医学院附属瑞金医院功能神经外科;
【基金】：国家自然科学基金(81271518,81471387) 上海交通大学医学院-中国科学院神经科学研究所脑疾病临床研究中心项目~~
【分类号】：R749.7

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