路易体痴呆与帕金森病痴呆认知及精神行为比较

发布时间：2018-03-17 07:11

本文选题：路易体痴呆　切入点：帕金森病　出处：《实用医学杂志》2017年23期 　论文类型：期刊论文

【摘要】：目的探讨路易体痴呆(DLB)和帕金森病痴呆(PDD)认知及精神行为特点。方法对48例DLB患者和38例PDD患者进行运动症状评估、认知评估及精神行为症状评估。结果 DLB组首发症状单侧起病和震颤起病较PDD患者少,震颤评分较PDD患者低,但姿势步态障碍评分较PDD患者高。DLB组认知评分明显低于PDD组,DLB组在视空间和执行、注意力及定向力方面评分低于PDD组。幻觉是DLB最常见的精神症状,81.3%的DLB患者有幻觉,易激惹、情绪不稳也是DLB常见的精神症状(62.5%)。PDD患者中淡漠、抑郁和焦虑较DLB患者更常见。结论 DLB患者认知障碍较PDD进展快,存在明显幻觉及易激惹、情绪不稳,而PDD患者存在明显的淡漠、抑郁和焦虑。
[Abstract]:Objective to investigate the cognitive and psychobehavioral characteristics of Louis body dementia (DLB) and Parkinson's disease dementia (PD). Methods the motor symptoms of 48 patients with DLB and 38 patients with PDD were evaluated. Results in DLB group, the initial symptoms of unilateral onset and tremor were less than those of PDD, and the score of tremor was lower than that of PDD. However, the scores of postural gait disorders in the DLB group were significantly lower than those in the PDD group. The scores of visual space and executive, attention and orientation in the PDD group were lower than those in the PDD group. 81.3% of the DLB patients with hallucination, the most common mental symptom of DLB, had hallucinations and were easily irritated. Emotional instability is also a common mental symptom of DLB. Depression and anxiety are more common in patients with DLB than in patients with DLB. Conclusion Cognitive impairment in DLB patients is faster than that in PDD patients, and there are obvious hallucinations, irritability and emotional instability in DLB patients. PDD patients had significant apathy, depression and anxiety.
【作者单位】：天津建华医院精神科;天津市环湖医院神经内科;
【基金】：国家自然科学基金面上项目(编号:81571057) 天津科技计划项目(编号:16ZXMJSY00010)
【分类号】：R749.1

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