尼麦角林联合高压氧治疗对血管性痴呆患者认知功能的影响研究

发布时间：2018-03-25 21:02

本文选题：尼麦角林　切入点：高压氧　出处：《重庆医学》2014年33期

【摘要】：目的探讨尼麦角林联合高压氧(HBO)治疗对血管性痴呆(VD)患者认知功能的影响。方法选取该院于2010年5月至2012年5月收治的60例VD患者,分为试验组(n=30)和对照组(n=30)。2组患者均给予血管性痴呆的常规处理,并且结合患者的血压血糖情况给予相应的控制血糖及血压治疗。并且两组均接受尼麦角林治疗,试验组同时加用HBO治疗。治疗前、治疗后第8、16周均采用简易智能状态量表(MMSE)以及日常生活能力量表(ADL)来评判其临床疗效。结果治疗前及治疗后第8周,试验组MMSE和ADL评分与对照组比较,差异无统计学意义(P0.05);治疗后第16周,试验组MMSE和ADL评分明显著高于对照组(P0.05)。治疗过程中,没有失访以及死亡情况的发生。结论 HBO治疗有益于改善VD患者的认知功能,并且能够有效提高患者的生活质量。
[Abstract]:Objective to investigate the effect of nicergoline combined with HBO on cognitive function of vascular dementia patients with VD.Methods 60 patients with VD were treated in our hospital from May 2010 to May 2012. Two groups were divided into two groups: the experimental group and the control group. The patients in the control group were given the routine treatment of vascular dementia, and the patients were given corresponding blood glucose control and blood pressure treatment combined with the blood glucose status of the patients, and both groups were treated with niergoline. The trial group was treated with HBO at the same time. MMSE and ADL were used to evaluate the clinical efficacy before and after 8 weeks of treatment. Results before treatment and 8 weeks after treatment, the patients in the trial group were evaluated with the simple Mental State scale (MMSE) and the activity of Daily living scale (ADL). The scores of MMSE and ADL in the trial group were significantly higher than those in the control group at the 16th week after treatment, and the scores of MMSE and ADL in the experimental group were significantly higher than those in the control group. Conclusion the treatment of HBO is beneficial to improve the cognitive function of VD patients and can effectively improve the quality of life of patients with VD.
【作者单位】：广西医科大学第四附属医院神经内科;
【分类号】：R749.1

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