正常甲状腺功能与老年人轻度认知功能损害的相关性

发布时间：2018-04-03 16:26

  本文选题：轻度认知功能损害　切入点：促甲状腺激素　出处：《中国老年学杂志》2017年08期

【摘要】：目的探讨正常甲状腺功能对老年人认知功能的影响,明确甲状腺功能是否为老年人轻度认知功能损害(MCI)的危险因素。方法MCI患者和认知功能正常人各80例,空腹抽血测血清促甲状腺激素(TSH)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、血糖、血脂、血尿酸(UA),测量身高、体重和血压。分析甲状腺功能与认知功能的相关性及老年人MCI的危险因素。结果 TSH与老年人MMSE评分负相关(B=-1.6,P=0.000),FT4则与其正相关(B=2.2,P=0.04),FT3与其无显著相关;正常高TSH组的MMSE评分明显低于TSH中间组(P0.05);Logistic回归分析发现TSH和FT4是老年人MCI的影响因素。结论老年人正常范围内甲状腺功能轻度降低可以影响认知功能。
[Abstract]:Objective to investigate the effect of normal thyroid function on cognitive function in the elderly and to determine whether thyroid function is a risk factor for mild cognitive impairment (MCI) in the elderly.Methods Serum thyrotropin (TSH), free triiodothyronine (FT3), free thyroxine (FT4), blood glucose, blood lipid and serum uric acid were measured in 80 patients with MCI and 80 patients with normal cognitive function. Height, weight and blood pressure were measured.To analyze the correlation between thyroid function and cognitive function and the risk factors of MCI in the elderly.缁撴灉 TSH涓庤，

本文编号：1705981