胞二磷胆碱联合葛根素治疗血管性痴呆疗效观察

发布时间：2018-04-04 20:44

本文选题：血管性痴呆　切入点：胞二磷胆碱　出处：《中国动脉硬化杂志》2014年10期

【摘要】：目的探讨胞二磷胆碱与葛根素在血管性痴呆患者中联合应用的意义。方法选择2008年2月~2013年2月期间收治的血管性痴呆患者112例,采用区组化随机分组法将入选对象随机分为观察组和对照组,每组56例,两组患者均采用胞二磷胆碱治疗,而观察组患者在此基础上加用葛根素治疗,并分别对两组患者的临床治疗情况、HDS评分情况、临床指标改善情况进行比较和分析。结果与对照组患者相比,观察组患者临床治疗显效率和总有效率均显著升高,同时无效比率则显著减少,差异有统计学意义(P0.05);观察组患者治疗后HDS评分值较对照组明显提高,差异有统计学意义(P0.05);观察组患者治疗后平均血流速度(VM)和动脉指数(PI)较对照组均明显好转,差异有统计学意义(P0.05)。结论胞二磷胆碱联合葛根素在短期内能够积极促进血管性痴呆患者临床治疗效果的全面改善。
[Abstract]:Objective to investigate the cell two choline and Puerarin Combined with application significance in patients with vascular dementia. Methods 112 patients with vascular dementia from February 2008 ~2013 year in February period, using block randomization method, the selected subjects were randomly divided into observation group and control group, 56 cases in each group, two groups of patients were treated with cell two choline treatment, while the patients in the observation group on the basis of Puerarin Treatment, and clinical treatment of two groups of patients, HDS score, improvement of clinical indicators were compared and analyzed. Results compared with the control group, the observation group of patients with clinical treatment effective rate and total effective rate were significantly increased at the same time, invalid ratio is significantly reduced, the difference was statistically significant (P0.05); patients in the observation group after treatment HDS score increased significantly compared with the control group, the difference was statistically significant (P0.05); patients in the observation group after treatment level The mean blood flow velocity (VM) and arterial index (PI) were significantly better than those in the control group (P0.05). Conclusion the two phosphorous choline combined with Puerarin can promote the clinical treatment of vascular dementia in a short time.

【作者单位】：山东省医学科学院附属医院内科;
【分类号】：R749.13

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