慢性疲劳综合征与抑郁症、焦虑症患者临床症状的差异

发布时间：2018-04-14 22:41

本文选题：慢性疲劳综合征 + 抑郁症　；参考：《中国康复理论与实践》2014年06期

【摘要】：目的分析研究慢性疲劳综合征(CFS)与轻中度抑郁症、焦虑症患者疲劳特征及抑郁、焦虑症状的差异。方法运用疲劳量表-14(FS-14)、汉密尔顿抑郁量表(HAMD)和汉密尔顿焦虑量表(HAMA)对182例CFS及轻中度抑郁症、焦虑症患者进行测评及统计分析。结果三组患者在躯体疲劳程度、精神疲劳程度及疲劳总分各方面均无显著性差异(P0.05);CFS组患者可能有抑郁症状的患者为39例(62.9%),伴有轻中度抑郁症状的患者为23例(37.1%),未发现肯定没有抑郁症状的患者;CFS组患者可能有焦虑症状的46例(74.2%),肯定有焦虑症状的16例(25.8%),未发现肯定没有焦虑症状的患者;CFS组HAMD总分显著低于轻中度抑郁症组(P0.001),两组在焦虑/躯体化、阻滞两因子中有非常显著性差异(P0.01),在认识障碍、日夜变化、绝望感各因子中有显著性差异(P0.05)。CFS组HAMA总分显著低于轻中度焦虑症组(P0.001),两组在精神性焦虑方面有非常显著性差异(P0.01),在躯体性焦虑各方有显著性差异(P0.05)。结论 CFS与轻中度抑郁症、焦虑症三组患者在临床中均表现为"郁"与"疲"的同时存在,在临床症状的表现上存在着一定的"相互重叠"现象。
[Abstract]:Objective to study the difference between chronic fatigue syndrome (CFS) and mild to moderate depression and anxiety.Methods A total of 182 patients with CFS and mild to moderate depression and anxiety were assessed and statistically analyzed by using fatigue scale -14 (FS-14), Hamilton Depression scale (Hamd) and Hamilton anxiety scale (Hama).Results the degree of somatic fatigue in the three groups,There was no significant difference in the degree of mental fatigue and the total score of fatigue in all aspects. In the CFS group, there were 39 patients with depression and 23 patients with mild and moderate depressive symptoms.There were 46 patients with anxiety symptoms in group A and 16 patients with certain symptoms of anxiety. The total score of HAMD in patients without anxiety symptoms was significantly lower than that in patients with mild to moderate depression (P 0.001), and anxiety / somatization was found in both groups.There is a very significant difference between the two factors of blocking P0.01, which changes in cognitive impairment, day and night,The total score of HAMA in the group of hopelessness was significantly lower than that in the group of mild to moderate anxiety disorder (P 0.001). There was a very significant difference in mental anxiety between the two groups (P 0.01), and there was a significant difference between the two groups in terms of somatic anxiety (P 0.05).Conclusion the clinical manifestations of CFS and mild to moderate depression and anxiety disorder are both "depression" and "fatigue", and there is a certain overlap in the clinical symptoms.
【作者单位】：上海中医药大学附属岳阳医院中医内科;上海中医药大学;
【基金】：国家自然基金项目(No.81173227) 国家中医药管理局“十二五”中医药重点学科建设“中医治未病学”项目上海市中医药事业发展三年行动计划(传统医学示范中心建设项目)(No.ZYSNXD-YL-CTXK) 上海岳阳医院慢性疲劳综合征重点专病建设项目
【分类号】：R749.4

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