缺血性脑卒中继发轻度认知功能障碍的影响因素分析

发布时间：2018-04-17 23:28

本文选题：缺血性脑卒中 + 认知功能障碍　；参考：《山东医药》2017年16期

【摘要】：目的探讨缺血性脑卒中继发轻度认知功能障碍(MCI)的影响因素。方法对81例缺血性脑卒中患者随访3个月,其中认知功能正常36例、继发MCI 45例。分析患者入院后头颅MRI检查结果,对患者的病变部位、病灶数量、病变性质等资料进行单因素及多因素Logistic回归分析。结果单因素Logistic回归分析结果显示,病变部位为左额叶、左颞叶、左枕叶、下丘脑、后丘脑及存在多发病灶、脑白质病变、脑萎缩与缺血性脑卒中继发MCI有关(P均0.05)。多因素Logistic回归分析结果显示,病变部位为左额叶(β=0.312,OR=1.502)、左枕叶(β=0.326,OR=1.546)、下丘脑(β=0.394,OR=1.698)及存在多发病灶(β=0.616,OR=1.901)、脑白质病变(β=0.506,OR=1.759)是缺血性脑卒中患者继发MCI的独立危险因素(P均0.05)。结论病变部位为左额叶、左枕叶、下丘脑及存在多发病灶、脑白质病变是缺血性脑卒中患者继发MCI的危险因素。
[Abstract]:Objective to investigate the influencing factors of mild cognitive impairment (MCI) in ischemic stroke.Methods 81 patients with ischemic stroke were followed up for 3 months, including 36 cases with normal cognitive function and 45 cases with secondary MCI.The results of head MRI after admission were analyzed. The location, number and nature of lesions were analyzed by univariate and multivariate Logistic regression analysis.Results univariate Logistic regression analysis showed that the lesions were located in the left frontal lobe, left temporal lobe, left occipital lobe, hypothalamus, posterior thalamus and multiple lesions, white matter lesions, atrophy and secondary MCI related to ischemic stroke (P 0.05).The results of multivariate Logistic regression analysis showed that the location of the lesion was left frontal lobe (尾 -0.312), left occipital lobe (尾 ~ 0.326), hypothalamus (尾 ~ (0.394) O ~ (1.698)) and multiple lesions (尾 ~ (0.616) O ~ (1.901), 尾 ~ (0.506) OR1.759) as independent risk factors for secondary MCI in patients with ischemic stroke (P < 0.05).Conclusion the lesions are located in the left frontal lobe, left occipital lobe, hypothalamus and multiple lesions. White matter lesions are the risk factors for secondary MCI in ischemic stroke patients.
【作者单位】：梧州市工人医院广西医科大学第七附属医院;
【基金】：梧州市科学研究与技术开发计划项目(201302054)
【分类号】：R749.13

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