老年腔隙性脑梗死患者轻度血管性认知功能障碍分析

发布时间：2018-05-16 00:40

本文选题：老年人 + 腔隙性脑梗死　；参考：《现代预防医学》2014年04期

【摘要】：目的对老年腔隙性脑梗死(LI)患者进行认知功能的评价,探讨患者认知功能障碍的特点,为今后临床采取干预措施提供依据。方法某院神经内科收治的老年腔隙性脑梗死患者作为调查对象,采用蒙特利尔智能评价量表(MOCA)对对照组及LI组患者进行调查评估,同时评价不同病变部位与认知功能受损的情况。结果 LI组与对照组的MoCA得分比较发现,总体认知情况(MoCA)、视空间与执行、命名、注意、计算、语言、抽象、延迟回忆与定向均有统计学差异(P0.01),各项认知功能均有受损。不同病灶部位患者的MoCA得分情况与对照组进行比较发现,额叶深部、基底节区及颞叶病变对认知功能的影响较大,各部位评分与对照组比较差异有统计学意义(P0.05)。结论老年患者发生腔隙性脑梗死对认知功能各方均有一定影响,尤其是病灶部位位于额叶深部、基底节及颞叶时对认知功能影响更为明显。
[Abstract]:Objective to evaluate the cognitive function of senile patients with lacunar infarction (Li) and to explore the characteristics of cognitive dysfunction in order to provide evidence for clinical intervention in the future. Methods elderly patients with lacunar cerebral infarction treated in a department of neurology were investigated and evaluated with the Montreal Intelligent Evaluation scale (MOCA) in the control group and Li group. At the same time, the different lesion sites and cognitive impairment were evaluated. Results the MoCA scores of Li group and control group were compared with that of control group. The results showed that there were significant differences in total cognitive status, visual space and execution, naming, attention, calculation, language, abstraction, delayed recall and orientation (P0.01), and all cognitive functions were impaired. The MoCA scores of patients with different lesion sites were compared with those of the control group. It was found that the deep frontal lobe, basal ganglia and temporal lobe lesions had a great influence on cognitive function, and there was significant difference in the scores of different sites compared with the control group (P 0.05). Conclusion the occurrence of lacunar cerebral infarction in elderly patients has a certain effect on cognitive function, especially when the lesion is located in the deep frontal lobe, especially in basal ganglia and temporal lobe.
【作者单位】：武警广东总队医院神经内科;武警广东总队医院心血管内科;
【分类号】：R749.1;R743.3

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