中医综合疗法联合西药治疗血管性痴呆103例临床观察

发布时间：2018-05-23 07:45

本文选题：血管性痴呆 + 中医综合疗法　；参考：《中医杂志》2014年23期

【摘要】：目的观察中医综合疗法联合西药治疗血管性痴呆的临床疗效。方法采用多中心、随机对照试验的设计方法,将218例患者分为治疗组110例和对照组108例。两组均给予内科基础治疗,治疗组同时给予中医综合治疗方案(中医辨证治疗、针刺、康复训练、护理);对照组同时口服盐酸多奈哌齐片,每日5 mg,4周后增至10 mg,康复训练及护理同治疗组,两组均治疗2个月。治疗前后采用简易精神状态检查表(MMSE)评价患者认知功能,采用Blessed行为量表(BBS评分)评价患者行为能力,治疗后判断其临床疗效。结果治疗组认知功能疗效总有效率为68.93%,对照组为57.00%;治疗组行为能力疗效总有效率为70.87%,对照组为61.00%。两组均可以明显改善MMSE评分及BBS评分(P0.05或P0.01),且治疗组的作用明显优于对照组(P0.05或P0.01)。结论中医综合疗法能显著改善血管性痴呆患者的认知功能和行为能力,提高临床疗效。
[Abstract]:Objective to observe the clinical effect of combination therapy of traditional Chinese medicine and western medicine on vascular dementia. Methods 218 patients were divided into treatment group (n = 110) and control group (n = 108). Both groups were given basic medical treatment, while the treatment group was given comprehensive treatment of TCM (TCM syndrome differentiation, acupuncture, rehabilitation training, nursing care), while the control group was orally administered with Donepezil Hydrochloride tablets at the same time. It was increased to 10 mg after 4 weeks. Rehabilitation training and nursing were treated for 2 months in the same treatment group. Before and after treatment, the patients' cognitive function was evaluated by simple mental state test (MMSE), and the patients' behavioral ability was evaluated by Blessed behavior scale (BBS). The clinical efficacy was evaluated after treatment. Results the total effective rate of cognitive function was 68.93 in the treatment group, 57.00 in the control group, 70.87 in the treatment group and 61.00 in the control group. MMSE score and BBS score were significantly improved in both groups, and the effect of the treatment group was significantly better than that of the control group (P0.05 or P0.01). Conclusion the comprehensive therapy of TCM can significantly improve the cognitive function and behavioral ability of patients with vascular dementia and improve the clinical efficacy.
【作者单位】：广西中医药大学第一附属医院;广西中医药大学;广西医科大学第一附属医院;南宁市中医院;柳州市中医院;
【基金】：广西科学研究与技术开发计划资助项目(桂科攻1298003-6-5)
【分类号】：R749.13

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