孤独症男童生长发育及头面部表型特征分析

发布时间：2018-05-24 22:40

本文选题：孤独 + 生长和发育　；参考：《中国学校卫生》2014年11期

【摘要】：目的了解男性孤独症患儿基本生长发育指标和头面部表型特征,为儿童孤独症的早期诊断提供参考依据。方法整群抽取天津市区6所特殊教育学校的60名男性孤独症患儿,以天津市1所幼儿园40名4~7岁身体和心理发育均正常的男童作为对照,测量形态发育、生理功能及头面部表型指标。结果 10~12岁男性孤独症患儿平均皮褶厚度低于正常男生,13~15岁组平均体重和维尔维克指数均高于正常男生(t值分别为-3.858,2.196,2.461,P值均0.05)。16~18岁组收缩压均值低于正常男生(t=-2.798,P=0.038)。3~8岁孤独症男童唇高、口宽均值分别为(18.5±2.38)(38.1±3.73)mm,大于正常儿童的(16.3±2.67)(35.5±3.98)mm,差异均有统计学意义(t值分别为3.017,2.316,P值均0.05)。结论男性孤独症患儿体格发育较正常差,并可能存在面部表型的特异性。应加强对此特殊人群的体质测试研究。
[Abstract]:Objective to investigate the basic growth and development indexes and facial phenotypic characteristics of male autistic children, and to provide reference for early diagnosis of autistic children. Methods 60 male autistic children were selected from 6 special education schools in Tianjin, and 40 boys with normal physical and mental development were selected from a kindergarten in Tianjin as a control group, and their morphological development was measured. Physiological function and phenotypic index of head and face. Results the average skinfold thickness of 10 ~ 12 year old male autistic children was lower than that of normal boys (1315 years old), the average body weight and Wilwick index were higher than those of normal boys (-3.858 卤2.196 ~ 2.461g P, P = 0.05). The mean systolic blood pressure of 18 years old group was lower than that of normal boys (-2.798P0.0388.38 years old), and the mean value of systolic blood pressure (SBP) in 18 years old group was lower than that in normal boys (-2.798P0.0380.38 years old). The mean width of mouth was 18.5 卤2.38.1 卤3.73mm, which was higher than that of normal children (16.3 卤2.67g / 35.5 卤3.98mm). The difference was statistically significant (P = 3.017 卤2.316g, P < 0.05). Conclusion the physical development of male autistic children is worse than that of normal children, and there may be facial phenotypic specificity in male autistic children. We should strengthen the physique test of this special population.
【作者单位】：天津医科大学公共卫生学院;
【基金】：国家自然科学基金项目(81072313)
【分类号】：R749.94

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