WONCA研究论文摘要汇编——阿片类药物成瘾和使用过量:医生在社区应用纳洛酮的经验、态度和喜好

发布时间：2018-05-30 20:28

本文选题：纳洛酮治疗 + 阿片类药物成瘾　；参考：《中国全科医学》2017年15期

【摘要】：背景爱尔兰每年因阿片类药物使用过量导致的死亡超过200例。纳洛酮及阿片类药物过量用药的预防和管理应成为医疗管理优先考虑的内容。纳洛酮可有效治疗阿片类药物过量使用,目前正在考虑是否可以在无医嘱情况下更广泛地使用纳洛酮。目的明确和丰富全科医生对阿片类药物成瘾、过量服用和纳洛酮供应的观点和经验。设计与场所对隶属于爱尔兰都柏林大学全科医学系的全科医生进行匿名问卷调查。方法共有714例全科医生受邀完成匿名问卷调查,将其结果与同期全科医生实习生的调查结果进行比较。结果 714例受试者中,共有448例(62.7%)做出回应。1/3的全科医生在城市、农村和城乡混合区。75%以上做出回应的全科医生的患者有不正当使用阿片类药物经历,25%的全科医生开出美沙酮处方。1/3的全科医生赞成在社区增加纳洛酮的使用量;1/3的人愿意参加这样一个计划。与合格的全科医生相比,采用纳洛酮治疗阿片类药物过量使用、愿意参与纳洛酮给药的全科医生实习生的比例更高。纳洛酮鼻内用药优于单次(P0.001)或多剂量的(P0.001)肌肉注射。66.1%(n=292)的全科医生赞同更广泛地使用纳洛酮。结论全科医生认为有大量人群存在阿片类药物使用障碍,但仍对其采用阿片类药物激动剂治疗。全科医生支持纳洛酮的广泛使用,并将参与其扩展使用。因此迫切需要开展和评估支持基于全科医生分配给药的实施战略。
[Abstract]:Background more than 200 deaths are caused by opioid overdose in Ireland each year. The prevention and management of naloxone and opioid overdose should be the priority of medical management. Naloxone is effective in the treatment of opioid overdose, and consideration is being given to the possibility of using naloxone more widely without medical advice. Objective to clarify and enrich the views and experiences of general practitioners on opioid addiction, overdose and naloxone supply. An anonymous questionnaire survey was conducted among general practitioners in the Department of General Medicine, University of Dublin, Ireland. Methods A total of 714 general practitioners were invited to complete anonymous questionnaires. Results A total of 448 out of 714 subjects responded to a third of the general practitioners in the city. More than .75% of responding general practitioners in rural and urban areas have had inappropriate use of opiates, 25% of general practitioners have prescribed methadone. 1 / 3 of general practitioners are in favour of increasing naloxone use in the community by 1 / 3. Ten percent of people are willing to take part in such a plan. Compared with qualified general practitioners, a higher proportion of interns were willing to take part in naloxone administration in the treatment of opioid overdose with naloxone. Naloxone intranasal medication is better than single dose of P0.001) or multiple dose of P0.001) intramuscular injection of .66.1 and naloxone 292) in favor of wider use of naloxone. Conclusion the general practitioners believe that a large number of people have opioid drug use disorders, but they still use opioid agonists. General practitioners support the widespread use of naloxone and will be involved in its expanded use. Therefore, there is an urgent need to develop and evaluate implementation strategies to support GP-based drug delivery.
【分类号】：R749.6

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