认知障碍初步评价表信度与效度的初步研究

发布时间：2018-06-07 01:06

  本文选题：认知障碍 + 阿尔茨海默病　； 参考：《中华老年心脑血管病杂志》2014年10期

【摘要】：目的对认知障碍初步评价表(COG-12)在阿尔茨海默病(AD)患者中的信度与效度进行评价。方法选择2013年1~12月就诊于南京医科大学附属脑科医院老年精神科的AD患者148例为AD组,另选择社区志愿者365例为对照组,2组均接受临床痴呆量表、AD8、简易智能状态检查量表、画钟测验评估和COG-12测评。其中100例AD患者知情者在首次评定1个月内重测COG-12。结果 COG-12的克朗巴赫α系数=0.883,重测信度=0.883(P0.01)。COG-12各条目评分与总分的相关系数为0.41~0.79(P0.05,P0.01);COG-12总分与简易智能状态检量表、画钟测验呈负相关(r=-0.67,r=-0.27,P0.01),与临床痴呆量表、AD8总分呈正相关(r=0.80,r=0.81,P0.01)。COG-12鉴别认知正常与轻度AD患者的ROC曲线下面积=0.902,≥6分为认知损害的界限分值敏感性为90.0%,特异性为82.5%;鉴别轻度与中度AD患者的ROC曲线下面积=0.898,敏感性为90.5%,特异性为76.7%。结论 COG-12具有良好的信度和效度,是快速识别痴呆及评估严重程度敏感而准确的筛查评估工具。
[Abstract]:Objective to evaluate the reliability and validity of COG-12 in patients with Alzheimer's disease (AD). Methods from January to December 2013, 148 AD patients in the Department of Geriatrics and Psychiatry, affiliated brain Hospital of Nanjing Medical University were selected as AD group, and 365 community volunteers as control group. Clock drawing test evaluation and COG-12 evaluation. In 100 AD patients, COG-12 was re-tested within 1 month after the first assessment. Results the correlativity coefficient of COG-12 's Cronbach 伪 coefficient was 0.883.The correlation coefficient between each item score and the total score of the retest reliability was 0.883U P0.01U .COG-12 and the correlation coefficient of each item score and the total score of each item was 0.41 / 0.79P0.05P0.05P0.01and the simple intelligence state examination scale. The bell drawing test was negatively correlated with the total score of clinical dementia scale (AD8), and positively correlated with the total score of clinical dementia scale (AD8). The area under the ROC curve was 0.902 in patients with cognitive normal and mild AD, and the sensitivity of the threshold of 鈮，

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