认知行为治疗对未服药强迫障碍患者的大样本病例研究

发布时间：2018-06-13 23:09

本文选题：认知行为治疗 + 强迫障碍　；参考：《中国临床心理学杂志》2017年02期

【摘要】：目的:验证操作手册指导下的认知行为治疗(CBT)对未服药强迫障碍(OCD)患者的疗效、可接受性及适用性。方法:纳入符合DSM-IV强迫障碍诊断标准的门诊患者46例,在CBT操作手册指导下进行为期12周共14次个别CBT治疗。应用耶鲁-布朗强迫量表(Y-BOCS)、汉密尔顿抑郁量表(HAMD-17项)和汉密尔顿焦虑量表(HAMA)进行疗效评估,并采用0-10分的视觉模拟评分法来进一步评估患者对CBT的满意度和主观有益性。研究期间不服用任何精神药物。结果:39例患者完成了14次治疗(脱落率为15.22%),对完成治疗者进行治疗前后Y-BOCS,HAMA,HAMD分值的配对t检验,结果具有显著性差异(P均小于0.01)。按照意向性治疗统计方法,有效率为69.57%(32/46),完全缓解率为21.74%(10/46),OCD患者对CBT治疗的满意度为6.89±0.42,主观有益性为6.62±0.68。结论:手册指导下的单一CBT治疗对中国OCD患者具有较好的疗效,且可接受性高,治疗依从性好。
[Abstract]:Objective: to verify the efficacy, acceptability and applicability of cognitive behavioral therapy (CBT) under the instruction of manual for OCD-free obsessive-compulsive disorder (OCD). Methods: Forty-six outpatients who met the diagnostic criteria of DSM-IV obsessive-compulsive disorder were treated with 14 individual CBT treatments for 12 weeks under the guidance of CBT manual. The curative effect was evaluated with Y-BOCSA, Hamilton Depression scale (HAMD-17) and Hamilton anxiety scale (Hamma). The satisfaction and subjective usefulness of CBT were further evaluated by visual analogue score with 0-10 scores. No psychoactive drugs were taken during the study. Results 14 times of treatment were completed in 39 patients (abscission rate was 15.22%). The matched t test of Y-BOCSM Hama Hamd score before and after treatment was performed. The results showed that the difference was significant (P < 0.01). According to the statistical method of intentional therapy, the effective rate was 69.5732 / 46, and the complete remission rate was 21.7410 / 46 OCD patients' satisfaction with CBT treatment was 6.89 卤0.42, and subjective benefit was 6.62 卤0.68. Conclusion: the single CBT therapy under the guidance of manual has good curative effect, high acceptability and good therapeutic compliance for OCD patients in China.
【作者单位】：首都医科大学附属北京安定医院/临床心理学系;
【基金】：国家自然科学基金面上项目(白质与强迫障碍:认知行为治疗的靶点与机制81271493) 国家自然科学主任基金(强迫障碍认知行为治疗的神经影像学研究81141016)
【分类号】：R749.7

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