视觉P300电位在精神分裂症司法鉴定责任能力评定中的初步应用

发布时间：2018-07-26 12:10

【摘要】：目的探讨视觉P300在精神分裂症司法鉴定责任能力评定中的价值。方法分别对经司法鉴定为无责任能力的精神分裂症患者(n=68,无责任能力组)和限定责任能力的精神分裂症患者(n=59,限定责任能力组)进行视觉司法事件相关脑电位P300检测,以58名志愿受试者作为对照(正常组)。结果与正常组比较,无责任能力组和限定责任能力组P300电位成分中N1、N2和P3潜伏期显著延长(P0.01),P3波幅显著降低(P0.01)。无责任能力组P300电位成分中N1、N2和P3潜伏期较限定责任能力组显著延长,P3波幅则显著降低,组间比较差异均有统计学意义(P0.01)。结论视觉P300在精神分裂症司法鉴定责任能力评定中有一定的参考意义,但研究结果还有待进一步随访验证。
[Abstract]:Objective to explore the value of visual P300 in the evaluation of forensic responsibility for schizophrenia. Methods the visual judicial event-related brain potentials (P300) were measured in patients with schizophrenia (nong68) and those with limited ability of responsibility (nong59, limited responsibility ability group), respectively, who were identified as inresponsibility-incompetent by judicial identification. 58 volunteers were used as controls (normal group). Results compared with the normal group, the latency of N _ 1N _ 2 and P _ 3 in the P _ (300) potential in the non-responsibility ability group and the limited responsibility ability group were significantly prolonged (P0.01) and the amplitude of P _ (3) was significantly decreased (P _ (0.01). The latency of N _ 1N _ 2 and P _ 3 in the P300 potential components of the non-responsible ability group was significantly lower than that of the limited responsibility ability group, and the amplitude of P _ 3 wave was significantly decreased (P0.01). Conclusion Visual P300 has some reference significance in the evaluation of forensic responsibility of schizophrenia, but the results of the study need to be further followed up.
【作者单位】：上海交通大学医学院附属精神卫生中心;河南省精神病医院;
【基金】：上海市精神卫生中心院级课题(2011-YJ-09) 科技部“十二五”科技支撑计划(2012BAK16B04) 国家自然科学基金青年项目(81202388)~~
【分类号】：R749.3

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