磁共振波谱分析在帕金森病合并抑郁诊治中的应用
发布时间：2018-08-02 11:22
【摘要】：目的:研究帕金森病(PD)和帕金森病抑郁(DPD)患者磁共振波谱(MRS)的改变及其临床意义。方法:对23例PD患者和20例DPD患者进行MRS检测,对比分析两组患者额叶乙酰基天门冬氨酸(NAA)/肌酸复合物(Cr)和含胆碱化合物(Cho)/肌酸复合物(Cr)值的变化。结果 :H-YⅢ级和Ⅳ级DPD患者症状首发侧额叶的NAA/Cr值显著低于PD患者(P0.05),Cho/Cr值显著高于PD患者(P0.05);H-YⅠ级和Ⅱ级DPD患者症状首发侧额叶的NAA/Cr和Cho/Cr值与PD患者比较差异无统计学意义。结论:H-YⅢ级和Ⅳ级DPD患者额叶MRS有明显异常,提示MRS有助于DPD的诊治。
[Abstract]:Objective: to study the changes and clinical significance of magnetic resonance spectroscopy (MRS) in patients with Parkinson's disease (PD) and Parkinson's disease depression (DPD). Methods: MRS was detected in 23 patients with PD and 20 patients with DPD. The changes of (NAA) / creatine complex (Cr) and (Cho) / creatine complex (Cr) were compared between the two groups. Results the NAA/Cr value of the first frontal lobe in DPD patients with grade 鈪，
本文编号：2159270
[Abstract]:Objective: to study the changes and clinical significance of magnetic resonance spectroscopy (MRS) in patients with Parkinson's disease (PD) and Parkinson's disease depression (DPD). Methods: MRS was detected in 23 patients with PD and 20 patients with DPD. The changes of (NAA) / creatine complex (Cr) and (Cho) / creatine complex (Cr) were compared between the two groups. Results the NAA/Cr value of the first frontal lobe in DPD patients with grade 鈪，
本文编号：2159270
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