从心理理论能力看精神病高危综合征人群转归

发布时间：2018-08-09 15:39

【摘要】：目的探讨精神病高危综合征人群临床转归与其心理理论(theory of mind,To M)特征的关系。方法利用前驱期综合症结构式访谈(structured interview for psychosis-risk syndromes,SIPS)和前驱期综合症量表(scale of psychosis-risk symptoms,SOPS)筛选出精神病高危综合征(clinical high risk,CHR)者90例,用失言觉察任务(faux pas test,FPT)、眼神阅读测试(reading the mind in the eyes text,RMET)评估CHR者心理理论特征。进行为期2年随访,利用SIPS确定临床转归,根据精神病转归情况将CHR者分为转化组(20例)和未转化组(50例),对两组基线水平临床症状特征、FPT、RMET结果进行分析,比较其心理理论的差异。结果两组CHR者在基线水平临床症状差异无统计学意义(P0.05);在FPT中,两组CHR失言故事识别得分、失言故事理解得分和失言任务总分存在统计学差异(P0.05),在对照故事识别得分上无统计学差异(P0.05);两组RMET各结果无统计学差异(P0.05)。结论精神病高危人群心理理论能力受损严重个体精神病转化的风险更高。
[Abstract]:Objective to investigate the relationship between the clinical outcome and the characteristics of (theory of mindto M in patients with high risk psychiatric syndrome. Methods 90 patients with high risk psychiatric syndrome (clinical high riskkeratosus) were selected by using (structured interview for psychosis-risk syndrome structured interview and (scale of psychosis-risk symptoms syndrome scale (SMPs). (faux pas test and (reading the mind in the eyes text test were used to evaluate the psychological characteristics of CHR patients. The patients with SIPS were divided into two groups according to the outcome of psychosis: transforming group (n = 20) and non-transformed group (n = 50). To compare the difference of his theory of mind. Results there was no significant difference in clinical symptoms between the two CHR groups at baseline level (P0.05), while in FPT, the recognition scores of CHR gaffe stories in the two groups were not statistically significant (P0.05). There was statistical difference between the scores of understanding and task of miswords (P0.05), but there was no statistical difference in the scores of recognition of control stories (P0.05); there was no significant difference in the results of RMET between the two groups (P0.05). Conclusion there is a higher risk of psychosis transformation in individuals with impaired mental theoretical ability in high risk groups of mental illness.
【作者单位】：上海交通大学医学院附属精神卫生中心;
【基金】：国家自然科学基金(编号:81671329) 上海交通大学医工交叉基金(编号:YG2014MS40) 上海市科委西医引导类项目(编号:15411967200)
【分类号】：R749

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