贵州省美沙酮维持治疗门诊患者脱失影响因素分析

发布时间：2018-09-06 19:48

【摘要】：目的了解贵州省接受美沙酮维持治疗的患者接受治疗后的脱失情况,探讨与患者治疗脱失有关的危险因素,为提高贵州省的美沙酮维持治疗患者的保持率提供依据。方法对贵州省所有在2010年1月1日前开诊的门诊进行普查,利用"艾滋病综合防治信息系统"收集美沙酮维持治疗患者的数据资料,包括社会人口学情况、尿检、治疗及随访情况等,对19个因素进行χ2检验和Logistic回归多因素分析,以确定影响美沙酮维持治疗患者脱失的因素。结果共有2 955名接受美沙酮维持治疗的患者纳入分析,性别(χ2=49.749,P0.001)、年龄(χ2=70.003,P0.001)、吸毒方式(χ2=36.060,P0.001)、治疗剂量(χ2=105.598,P0.001)、尿吗啡检结果(χ2=167.165,P0.001)、与家人关系(χ2=1.785,P=0.410)对患者脱失的影响有统计学意义。结论有注射吸毒史、尿吗啡检测阳性、治疗剂量低等是美沙酮维持治疗患者脱失的主要危险因素。美沙酮门诊应进一步提高服务质量和治疗水平,建立有效的服药监督机制,针对不同患者制定相应的治疗措施,并给予患者后期心理辅导和行为干预,以提高患者的保持率。
[Abstract]:Objective To investigate the loss of methadone maintenance therapy (MMT) patients in Guizhou Province after treatment, and to explore the risk factors associated with MMT loss, so as to provide evidence for improving the maintenance rate of MMT patients in Guizhou Province. Data on methadone maintenance therapy were collected from 19 patients by_2 test and logistic regression analysis. Results A total of 2 955 patients received methadone maintenance therapy. Sex (2 = 49.749, P 0.001), age (2 = 70.003, P 0.001), drug use pattern (2 = 36.060, P 0.001), treatment dose (2 = 105.598, P 0.001), urinary morphine test results (2 = 167.165, P 0.001), and family relationship (2 = 1.785, P = 0) had statistical significance on the loss of patients. Positive results and low dosage of methadone are the main risk factors for the loss of methadone maintenance therapy patients. Rate.
【作者单位】：北京大学公共卫生学院;贵州省疾控中心艾防所;
【基金】：贵州省特助经费(TZJF-2011年-23号)
【分类号】：R749.64

【参考文献】